https://scholar.korea.ac.kr/handle/2021.sw.korea/2382 Thu, 09 Apr 2026 06:20:42 GMT 2026-04-09T06:20:42Z https://scholar.korea.ac.kr/handle/2021.sw.korea/200540 Title: Production of α-Glycerylphosphorylcholine in Fermented Roots, Tubers, and Fruits Authors: Tse, Timothy J.; Chicilo, Farley; Wiens, Daniel J.; Shen, Jianheng; Alegria, Javier Anleu; Kim, Young Jun; Hong, Ji Youn; Kim, Jae Kyeom; Shin, Eui-Cheol; Reaney, Martin J. T.; Shim, Youn Young Abstract: Vegetables and fruits, high in starch and sugars, are promising substrates for bioethanol production, but can also yield valuable nootropic compounds, such as alpha-glycerylphosphorylcholine (alpha-GPC). This compound is a known cognitive enhancer that works by increasing the release of acetylcholine, a neurotransmitter essential for learning and memory. In this study, select root and tuber crops, as well as fruits, were subjected to Saccharomyces cerevisiae fermentation to observe the co-production of ethanol and alpha-GPC. The ethanol yields from these substrates were comparable to those from wheat (var. AC Andrew), ranging from 30.44 g/L (beet) to 70.04 g/L (lotus root). Aside from ethanol, alpha-GPC was also produced, with purple top turnip yielding 0.91 g/L, the second highest concentration after wheat (used as a reference), which produced 1.25 g/L. Although alpha-GPC yields in the tested substrates were lower than those from cereal grains (e.g., wheat and barley), a noteworthy observation was the production of methanol in many of these substrates. Methanol was detected in all feedstocks except wheat, with concentrations ranging from 0.10 g/L (cassava) to 1.69 g/L (purple top turnip). A linear regression analysis revealed a strong correlation between methanol and alpha-GPC content (R2 = 0.876; slope = 0.52), suggesting a potential link in their biosynthetic pathways. These feedstocks not only proved effective as substrates for bioethanol production, but also showed potential for generating value-added compounds such as alpha-GPC. This dual-purpose potential presents new market opportunities for producers by leveraging both biofuel and nootropic compound production. Furthermore, the observed relationship between methanol and alpha-GPC production warrants further investigation to elucidate the metabolic pathways involved. Tue, 01 Oct 2024 00:00:00 GMT https://scholar.korea.ac.kr/handle/2021.sw.korea/200540 2024-10-01T00:00:00Z https://scholar.korea.ac.kr/handle/2021.sw.korea/199670 Title: Prediction model of browning inhibitor concentration and its optimal composition for mass processing of ready-to-eat fresh-cut 'Fuji' apple (<i>Malus domestica</i> Borkh.) strains Authors: Baek, Soo Min; Ahn, Sung-Il; Lee, Sang Hoon; Choi, Jae-Mun; Hong, Jiyoun; Kim, Young Jun; Han, Bok Kyung Abstract: In this study, we optimized the composition of the browning inhibitor for apples and established a prediction model for the browning inhibitor concentration in mass-processed fresh-cut apples based on electrical conductivity measurements. The "Fuji" apples that were harvested in Chungju, Korea, were used for this study. Vitamin C mixture (VCM) and trehalose (Tre) were used as browning inhibitors at a 4% ratio. The browning reaction under Delta 3 of BI (browning index) for 5 days was defined as the target shelf-life of the apple flesh. The Delta BI of VCM and Tre was lower than that of VCM by 4%. It is revealed that the electrical conductivity of the browning inhibitor was highly correlated with its concentration and the number of soaked apples. Finally, the regression of the conductivity was fitted as Y = -0.0024 (number of soaked apples) + 0.5111 (R-2 = 0.9931). In the validation test, the conductivity must be maintained at 0.4373 S/m or higher to maintain the target anti-browning level of Delta 3 or less, which corresponded to similar to 80% of the initial qualitative level after manufacture. The conductivity measurement of the browning inhibitor is suitable for monitoring and predicting its concentration in the mass processing of fresh-cut apple production due to the convenience of this method. Thu, 01 Aug 2024 00:00:00 GMT https://scholar.korea.ac.kr/handle/2021.sw.korea/199670 2024-08-01T00:00:00Z https://scholar.korea.ac.kr/handle/2021.sw.korea/197697 Title: Process evaluation of a mobile healthcare program among employees with overweight and obesity: a 12-week intervention study investigating the role of engagement Authors: Son, Imhuei; Hong, Jiyoun; Han, Young Hee; Gong, Bo Jeong; Zhang, Meng Yuan; Na, Woori; Sohn, Cheongmin; Hyun, Taisun Abstract: Objectives: A mobile health intervention program was provided for employees with overweight and obesity for 12 weeks, and a process evaluation was completed at the end of the program. We investigated participant engagement based on app usage data, and whether engagement was associated with the degree of satisfaction with the program. Methods: The program involved the use of a dietary coaching app and a wearable device for monitoring physical activity and body composition. A total of 235 employees participated in the program. App usage data were collected from a mobile platform, and a questionnaire survey on process evaluation and needs assessment was conducted during the post-test. Results: The engagement level of the participants decreased over time. Participants in their 40s, high school graduates or lower education, and manufacturing workers showed higher engagement than other age groups, college graduates, and office workers, respectively. The overall satisfaction score was 3.6 out of 5. When participants were categorized into three groups according to their engagement level, the upper group was more satisfied than the lower group. A total of 71.5% of participants answered that they wanted to rejoin or recommend the program, and 71.9% answered that the program was helpful in improving their dietary habits. The most helpful components in the program were diet records and a 1:1 chat with the dietary coach from the dietary coaching app. The barriers to improving dietary habits included company dinners, special occasions, lack of time, and eating out. The workplace dietary management programs were recognized as necessary with a need score of 3.9 out of 5. Conclusions: Participants were generally satisfied with the mobile health intervention program, particularly highly engaged participants. Feedback from a dietary coach was an important factor in increasing satisfaction. © 2023 Korean Society of Community Nutrition. Fri, 01 Dec 2023 00:00:00 GMT https://scholar.korea.ac.kr/handle/2021.sw.korea/197697 2023-12-01T00:00:00Z https://scholar.korea.ac.kr/handle/2021.sw.korea/196010 Title: Social cost-saving for health management of omega-3 fatty acid supplementation on cardiovascular disease in Korea Authors: Hong Ji Youn Fri, 20 Oct 2023 00:00:00 GMT https://scholar.korea.ac.kr/handle/2021.sw.korea/196010 2023-10-20T00:00:00Z