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A highly sensitive immunoassay using antibody-conjugated spherical mesoporous silica with immobilized enzymes

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dc.contributor.authorEum, Ji Young-
dc.contributor.authorHwang, Sang Youn-
dc.contributor.authorJu, Youngjun-
dc.contributor.authorShim, Jong Min-
dc.contributor.authorPiao, Yunxian-
dc.contributor.authorLee, Jinwoo-
dc.contributor.authorKim, Hak-Sung-
dc.contributor.authorKim, Jungbae-
dc.date.accessioned2021-09-05T16:53:14Z-
dc.date.available2021-09-05T16:53:14Z-
dc.date.created2021-06-15-
dc.date.issued2014-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/100995-
dc.description.abstractA highly sensitive immunoassay was developed by using antibody-conjugated spherical mesoporous silica with immobilized enzymes. The higher ratio of enzyme/antibody than conventional ELISA improved both the sensitivity and dynamic range. Especially, the use of spherical mesoporous silica could achieve a limit of detection (LOD) with a sensitivity that is 20 times more than that of ELISA using amorphous silica.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectELECTROCHEMICAL IMMUNOASSAY-
dc.subjectBIOFUEL CELLS-
dc.subjectNANOBIOCATALYSIS-
dc.subjectASSAY-
dc.subjectDNA-
dc.titleA highly sensitive immunoassay using antibody-conjugated spherical mesoporous silica with immobilized enzymes-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Jungbae-
dc.identifier.doi10.1039/c3cc48044e-
dc.identifier.scopusid2-s2.0-84896776799-
dc.identifier.wosid000332483200002-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.50, no.27, pp.3546 - 3548-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume50-
dc.citation.number27-
dc.citation.startPage3546-
dc.citation.endPage3548-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusELECTROCHEMICAL IMMUNOASSAY-
dc.subject.keywordPlusBIOFUEL CELLS-
dc.subject.keywordPlusNANOBIOCATALYSIS-
dc.subject.keywordPlusASSAY-
dc.subject.keywordPlusDNA-
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