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Detection of A beta plaques in mouse brain by using a disaggregation-induced fluorescence-enhancing probe

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dc.contributor.authorLee, Yeon Ok-
dc.contributor.authorShin, Jung-Won-
dc.contributor.authorYi, Chunsik-
dc.contributor.authorLee, Yun Hak-
dc.contributor.authorSohn, Nak-Won-
dc.contributor.authorKang, Chulhun-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-09-05T16:56:58Z-
dc.date.available2021-09-05T16:56:58Z-
dc.date.created2021-06-15-
dc.date.issued2014-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/101021-
dc.description.abstractWe herein report a fluorescence probe 1 capable of detecting water-soluble oligomeric Ab aggregates and A beta fibrils. Upon injection into A beta(42)-challenged mouse brains, probe 1 shows increased fluorescence intensity, indicating its facile binding to extracellular Ab fibrils in brain tissues.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectCONJUGATED POLYMERS-
dc.subjectALZHEIMERS-DISEASE-
dc.subjectAMYLOID PLAQUES-
dc.subjectPHOTOPHYSICS-
dc.subjectVISCOSITY-
dc.subjectANCA-
dc.titleDetection of A beta plaques in mouse brain by using a disaggregation-induced fluorescence-enhancing probe-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1039/c4cc02011a-
dc.identifier.scopusid2-s2.0-84899893546-
dc.identifier.wosid000335554300016-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.50, no.43, pp.5741 - 5744-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume50-
dc.citation.number43-
dc.citation.startPage5741-
dc.citation.endPage5744-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusCONJUGATED POLYMERS-
dc.subject.keywordPlusALZHEIMERS-DISEASE-
dc.subject.keywordPlusAMYLOID PLAQUES-
dc.subject.keywordPlusPHOTOPHYSICS-
dc.subject.keywordPlusVISCOSITY-
dc.subject.keywordPlusANCA-
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