Polymer-coated spherical mesoporous silica for pH-controlled delivery of insulin
- Authors
- Choi, Sae Rom; Jang, Dong-Jin; Kim, Sanghyun; An, Sunhyung; Lee, Jinwoo; Oh, Euichaul; Kim, Jungbae
- Issue Date
- 2014
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- JOURNAL OF MATERIALS CHEMISTRY B, v.2, no.6, pp.616 - 619
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF MATERIALS CHEMISTRY B
- Volume
- 2
- Number
- 6
- Start Page
- 616
- End Page
- 619
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/101086
- DOI
- 10.1039/c3tb21494j
- ISSN
- 2050-7518
- Abstract
- We report a pH-controlled insulin release system to provide an oral administration route. Mesoporous silica was chosen as a drug carrier, and pH-sensitive polymers were coated onto spherical mesocellular foam with pre-adsorbed insulin. We evaluated the insulin release in both acidic and neutral solutions to compare how this systembehaves under different pH conditions.
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- There are no files associated with this item.
- Appears in
Collections - College of Engineering > Department of Chemical and Biological Engineering > 1. Journal Articles
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