Vitamin D receptor FokI, BsmI, ApaI, and TaqI polymorphisms and the susceptibility to breast cancer: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Lee, Y. H. | - |
dc.contributor.author | Song, G. G. | - |
dc.date.accessioned | 2021-09-05T17:44:10Z | - |
dc.date.available | 2021-09-05T17:44:10Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0028-2685 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/101216 | - |
dc.description.abstract | The goal of this study is to examine whether vitamin D receptor (VDR) polymorphisms are associated with the susceptibility to breast cancer. Meta-analysis was employed to investigate the association between the VDR Fold, BsmI, ApaI, and TaqI polymorphisms and the incidence of breast cancer. A total of 32 comparative studies were evaluated in this meta-analysis, which included 17,067 patients and 20,843 controls. Meta-analysis of the VDR Fold polymorphism indicated an association between the incidence of breast cancer and the if genotype in Europeans (OR = 1.126, 95% CI = 1.026-1.243, p = 0.019) Furthermore, an association between the incidence of breast cancer and the VDR Fold polymorphism was found in the Europeans using the allele contrast, as well as the homozygote contrast. However, the meta-analysis indicated no association between breast cancer and the BsmI polymorphism in all study subjects, including the Europeans (OR for the B allele = 0.996, 95% CI = 0.964-1.097, p = 0.930, 1.026, 95% CI = 0.929-1.134, p = 0.610). Moreover, breast cancer incidence was not associated with the ApaI and Taq polymorphisms (OR for the A allele = 0.908, 95% CI = 0.763-1.041,p = 0.167, OR for the T allele = 0.972, 95% CI = 0.929-1.017,p = 0.221). This meta-analysis suggests that the VDR Fold polymorphism is associated with susceptibility to breast cancer in the European population. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AEPRESS SRO | - |
dc.subject | EPITHELIAL OVARIAN-CANCER | - |
dc.subject | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject | D-RELATED GENES | - |
dc.subject | POLISH POPULATION | - |
dc.subject | CAUCASIAN WOMEN | - |
dc.subject | VDR GENE | - |
dc.subject | RISK | - |
dc.subject | ASSOCIATION | - |
dc.subject | HAPLOTYPES | - |
dc.subject | CARCINOMA | - |
dc.title | Vitamin D receptor FokI, BsmI, ApaI, and TaqI polymorphisms and the susceptibility to breast cancer: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Y. H. | - |
dc.contributor.affiliatedAuthor | Song, G. G. | - |
dc.identifier.doi | 10.4149/neo_2014_077 | - |
dc.identifier.scopusid | 2-s2.0-84907296647 | - |
dc.identifier.wosid | 000342881900014 | - |
dc.identifier.bibliographicCitation | NEOPLASMA, v.61, no.5, pp.607 - 616 | - |
dc.relation.isPartOf | NEOPLASMA | - |
dc.citation.title | NEOPLASMA | - |
dc.citation.volume | 61 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 607 | - |
dc.citation.endPage | 616 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.subject.keywordPlus | EPITHELIAL OVARIAN-CANCER | - |
dc.subject.keywordPlus | SYSTEMIC-LUPUS-ERYTHEMATOSUS | - |
dc.subject.keywordPlus | D-RELATED GENES | - |
dc.subject.keywordPlus | POLISH POPULATION | - |
dc.subject.keywordPlus | CAUCASIAN WOMEN | - |
dc.subject.keywordPlus | VDR GENE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | HAPLOTYPES | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordAuthor | breast cancer | - |
dc.subject.keywordAuthor | vitamin D receptor | - |
dc.subject.keywordAuthor | polymorphism | - |
dc.subject.keywordAuthor | meta-analysis | - |
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