Oseltamivir-resistant influenza viruses isolated in South Korea from 2005 to 2010
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Han-Gil | - |
dc.contributor.author | Choi, Jang-Hoon | - |
dc.contributor.author | Lee, Hyun-Kyung | - |
dc.contributor.author | Mun, Su-Kyoung | - |
dc.contributor.author | Lee, Jong-Bok | - |
dc.contributor.author | Jho, Eek-Hoon | - |
dc.contributor.author | Kang, Chun | - |
dc.contributor.author | Lim, Young-Hee | - |
dc.date.accessioned | 2021-09-05T19:39:56Z | - |
dc.date.available | 2021-09-05T19:39:56Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2013-11 | - |
dc.identifier.issn | 0304-8608 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/101736 | - |
dc.description.abstract | South Korean isolates of oseltamivir-resistant influenza viruses from 2005-2010 were investigated with a total 491 influenza viruses identified from 1702 specimens. Neuraminidase genes from 342 influenza viruses (71 A/H1N1, 74 pandemic A/H1N1 2009, 117 A/H3N2, and 80 B) were analyzed by RT-PCR with molecular markers for oseltamivir resistance. The H274Y mutation in the NA protein was identified in 100 % (n=40) of A/H1N1 viruses circulating in 2008-2009. Influenza A/H1N1 viruses harboring the H274Y substitution exhibited, on average, a 626-fold reduction in oseltamivir susceptibility and clustered with the A/Norway/1736/2007 strain. Close and timely monitoring for resistance to clinically available influenza antivirals should be consistently performed. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER WIEN | - |
dc.subject | NEURAMINIDASE INHIBITORS | - |
dc.subject | UNITED-STATES | - |
dc.subject | B VIRUSES | - |
dc.subject | A H1N1 | - |
dc.subject | SURVEILLANCE | - |
dc.subject | INFECTIONS | - |
dc.subject | EMERGENCE | - |
dc.subject | WORLDWIDE | - |
dc.subject | SEASON | - |
dc.title | Oseltamivir-resistant influenza viruses isolated in South Korea from 2005 to 2010 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Young-Hee | - |
dc.identifier.doi | 10.1007/s00705-013-1734-3 | - |
dc.identifier.scopusid | 2-s2.0-84886645844 | - |
dc.identifier.wosid | 000326242300016 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF VIROLOGY, v.158, no.11, pp.2365 - 2370 | - |
dc.relation.isPartOf | ARCHIVES OF VIROLOGY | - |
dc.citation.title | ARCHIVES OF VIROLOGY | - |
dc.citation.volume | 158 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2365 | - |
dc.citation.endPage | 2370 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Virology | - |
dc.relation.journalWebOfScienceCategory | Virology | - |
dc.subject.keywordPlus | NEURAMINIDASE INHIBITORS | - |
dc.subject.keywordPlus | UNITED-STATES | - |
dc.subject.keywordPlus | B VIRUSES | - |
dc.subject.keywordPlus | A H1N1 | - |
dc.subject.keywordPlus | SURVEILLANCE | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | EMERGENCE | - |
dc.subject.keywordPlus | WORLDWIDE | - |
dc.subject.keywordPlus | SEASON | - |
dc.subject.keywordAuthor | Influenza viruses | - |
dc.subject.keywordAuthor | Neuraminidase | - |
dc.subject.keywordAuthor | Oseltamivir resistance | - |
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