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Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study

Authors
Seok, Dong KeunKee, Sae YoonKo, Soon YoungLee, Jung HwaKim, Hye YoungKim, In SunSeo, Hee Yeon
Issue Date
11월-2013
Publisher
SPANDIDOS PUBL LTD
Keywords
synchronous primary neoplasms; hematologic neoplasm; solid neoplasm
Citation
ONCOLOGY LETTERS, v.6, no.5, pp.1319 - 1322
Indexed
SCIE
SCOPUS
Journal Title
ONCOLOGY LETTERS
Volume
6
Number
5
Start Page
1319
End Page
1322
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/101778
DOI
10.3892/ol.2013.1580
ISSN
1792-1074
Abstract
Acute myeloid leukemia presenting as leukemia cutis (LC) with hepatocellular carcinoma is extremely rare. The current study presents a case of a 53-year-old male with generalized cutaneous nodules on the face and anterior chest wall. Laboratory tests, including bone marrow biopsy revealed acute myelomonocytic leukemia (AML-M4) with skin and tonsilar involvement. Liver magnetic resonance imaging (MRI) revealed a 6-cm mass in hepatic segments 4 and 8, and a liver biopsy demonstrated that hepatocellular carcinoma cells and immature blast cells coexisted. Although LC has been reported in Korea, a case of LC associated with acute myelomonocytic leukemia was diagnosed simultaneously with hepatocellular carcinoma and tonsillar involvement. The present study describes this case with a review of the literature.
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