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Cu2+-Responsive Bimodal (Optical/MRI) Contrast Agent for Cellular Imaging

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dc.contributor.authorJang, Joo Hee-
dc.contributor.authorBhuniya, Sankarprasad-
dc.contributor.authorKang, Jongeun-
dc.contributor.authorYeom, Areum-
dc.contributor.authorHong, Kwan Soo-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-09-05T21:18:01Z-
dc.date.available2021-09-05T21:18:01Z-
dc.date.created2021-06-15-
dc.date.issued2013-09-20-
dc.identifier.issn1523-7060-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/102139-
dc.description.abstractA water-soluble T-1 magnetic resonance imaging contrast agent (1) has been synthesized. The bimodal contrast agent 1 responds to the Cu2+ ion in living cells by enhancing the MRI modality signal whereas the optical signal gradually drops. This dual modality probe response depends on the cellular free copper ions in RAW 264.7 cells even at the micromolar level.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherAMER CHEMICAL SOC-
dc.subjectFLUORESCENT SENSOR-
dc.subjectCOPPER-
dc.subjectMECHANISMS-
dc.subjectDISEASES-
dc.titleCu2+-Responsive Bimodal (Optical/MRI) Contrast Agent for Cellular Imaging-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1021/ol4025293-
dc.identifier.scopusid2-s2.0-84884561319-
dc.identifier.wosid000330159700020-
dc.identifier.bibliographicCitationORGANIC LETTERS, v.15, no.18, pp.4702 - 4705-
dc.relation.isPartOfORGANIC LETTERS-
dc.citation.titleORGANIC LETTERS-
dc.citation.volume15-
dc.citation.number18-
dc.citation.startPage4702-
dc.citation.endPage4705-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.subject.keywordPlusFLUORESCENT SENSOR-
dc.subject.keywordPlusCOPPER-
dc.subject.keywordPlusMECHANISMS-
dc.subject.keywordPlusDISEASES-
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