Comparison of clinical outcomes between octogenarians and non-octogenarians with acute myocardial infarction in the drug-eluting stent era: Analysis of the Korean Acute Myocardial Infarction Registry
- Authors
- Yamanaka, Futoshi; Jeong, Myung Ho; Saito, Shigeru; Ahn, Youngkeun; Chae, Shung Chull; Hur, Seung Ho; Hong, Taek Jong; Kim, Young Jo; Seong, In Whan; Chae, Jei Keon; Rhew, Jay Young; Chae, In Ho; Cho, Myeong Chan; Bae, Jang Ho; Rha, Seung Woon; Kim, Chong Jin; Choi, Donghoon; Jang, Yang Soo; Yoon, Junghan; Chung, Wook Sung; Cho, Jeong Gwan; Seung, Ki Bae; Park, Seung Jung
- Issue Date
- 9월-2013
- Publisher
- ELSEVIER
- Keywords
- Elderly; Myocardial infarction; Treatment; Prognosis
- Citation
- JOURNAL OF CARDIOLOGY, v.62, no.3-4, pp.210 - 216
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CARDIOLOGY
- Volume
- 62
- Number
- 3-4
- Start Page
- 210
- End Page
- 216
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/102295
- DOI
- 10.1016/j.jjcc.2013.04.003
- ISSN
- 0914-5087
- Abstract
- Background and purpose: Octogenarians (age >= 80 years) with coronary artery disease constitute a high-risk group. However, octogenarian patients with acute myocardial infarction (AMI) in the drug-eluting stents (DES) era have not been widely reported. We aimed to identify clinical outcomes in octogenarian compared with non-octogenarian AMI patients. Methods and subjects: We retrospectively analyzed 9877 patients who underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and who were enrolled in the Korean Acute Myocardial Infarction Registry (KAMIR). They were divided into 2 groups, octogenarians (n=1494) and non-octogenarians (n=8383), in order to compare the incidence of 1-year all-cause death and 1-year major adverse cardiac events (MACE), where MACE included all-cause death, recurrent myocardial infarction, target vessel revascularization (TVR), target lesion revascularization (TLR), and coronary artery bypass grafting (CABG). Results: The clinical status was significantly inferior in octogenarians compared to non-octogenarians: Killip class >= II (34.8% vs. 22.5%, p<0.001), multivessel disease (65.8% vs. 53.7%, p<0.001). Rates of 1-year all-cause death were significantly higher in octogenarians than in non-octogenarians (22.3% vs. 6.5%, p<0.001). However, the rates of 1-year recurrent myocardial infarction (1.3% vs. 0.9%, p = 0.68), TLR (2.4% vs. 3.1%, p = 0.69), TVR (3.6% vs. 4.3%,p = 0.96), and CABG (0.9% vs. 0.9%, p=0.76) did not differ significantly between the 2 groups. Conclusions: Octogenarian AMI patients have higher rates of mortality and MACE even in the DES era. According to KAMIR subgroup analysis, the TLR/TVR rates in octogenarians were comparable to those in non-octogenarian AMI patients. (C) 2013 Published by Elsevier Ltd on behalf of Japanese College of Cardiology.
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