Implementation of a Biocircuit Implants for Neurotransmitter Release During Neuro-Stimulation

Abstract

Neurotransmitter assay of epinephrine (EP) was sought using a modified carbon nanotube paste electrode (PE). Using optimum conditions, cyclic voltammetry (CV) and the square wave (SW) stripping voltammetric working ranges were attained to 10-100 mgL(-1) (CV) and 20-140 ngL(-1) (SW). The relative standard deviation of 0.0549 (n = 15) was obtained at 20.0 mgL(-1) EP constant. Here, the analytical detection limit (S/N) was reached with 4.60 ngL(-1) (2.5x10(-11) molL(-1)) EP. The hand-made electrode was implanted into the in-vivo brain core of the animals and was used in chronoamperometric neuro detection. The results obtained are applicable in neuro sensing, physiological control, and other neuroscience fields.