Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Seung Chul | - |
dc.contributor.author | Ahn, Do Hwan | - |
dc.contributor.author | Kim, Su Jin | - |
dc.contributor.author | Lee, Hyoungseok | - |
dc.contributor.author | Oh, Tae-Jin | - |
dc.contributor.author | Lee, Jong Eun | - |
dc.contributor.author | Park, Hyun | - |
dc.date.accessioned | 2021-09-05T23:37:37Z | - |
dc.date.available | 2021-09-05T23:37:37Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-07-23 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102680 | - |
dc.description.abstract | Next-generation sequencing has become the most widely used sequencing technology in genomics research, but it has inherent drawbacks when dealing with high-GC content genomes. Recently, single-molecule real-time sequencing technology (SMRT) was introduced as a third-generation sequencing strategy to compensate for this drawback. Here, we report that the unbiased and longer read length of SMRT sequencing markedly improved genome assembly with high GC content via gap filling and repeat resolution. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | PYROSEQUENCING READS | - |
dc.subject | DNA | - |
dc.title | Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Hyun | - |
dc.identifier.doi | 10.1371/journal.pone.0068824 | - |
dc.identifier.scopusid | 2-s2.0-84880715396 | - |
dc.identifier.wosid | 000325211000041 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.8, no.7 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | PYROSEQUENCING READS | - |
dc.subject.keywordPlus | DNA | - |
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