Incidence and Risk Factors for Macular Hemorrhage Following Intravitreal Ranibizumab Injection for Neovascular Age-Related Macular Degeneration
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moon, Sang Woong | - |
dc.contributor.author | Oh, Jaeryung | - |
dc.contributor.author | Yu, Hyeong Gon | - |
dc.contributor.author | Cho, Hee Yoon | - |
dc.contributor.author | Song, Su Jeong | - |
dc.date.accessioned | 2021-09-06T00:13:02Z | - |
dc.date.available | 2021-09-06T00:13:02Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-07 | - |
dc.identifier.issn | 1080-7683 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/102834 | - |
dc.description.abstract | Purpose: To analyze the incidence of and risk factors for newly developed or increased macular hemorrhage after intravitreal ranibizumab injection (IVR) for neovascular age-related macular degeneration (AMD). Methods: We performed a retrospective chart review of 220 subjects (220 eyes) from 5 hospitals who received IVRs for neovascular AMD between 1 June 2009 and 30 June 2010. Systemic conditions (age, sex, presence of diabetes, hypertension, cardiovascular disease, smoking, and use of anticoagulation agent) and presence of hemorrhage at the initial exam were evaluated. The primary study outcome was the incidence of newly developed or increased macular hemorrhage during the 1-month postinjection period. Results: The incidence of newly developed or increased macular hemorrhage including vitreous hemorrhage was 8% (18/220). Presence of diabetes was found to be a risk factor for macular hemorrhage [odds ratios (OR): 2.16, 95% confidence intervals (CI): 1.07-8.13]. When subjects had both diabetes and hypertension, the risk of macular hemorrhage after injection increased 4.8-fold (OR: 4.84, CI: 1.24-18.85). Conclusion: The systemic condition of subjects was found to be an important risk factor for newly developed or increased macular hemorrhage after IVR for neovascular AMD. More consideration should be given to the status of diabetes and hypertension in subjects who receive ranibizumab for neovascular AMD. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.subject | THERAPY | - |
dc.subject | COMPLICATIONS | - |
dc.subject | EFFICACY | - |
dc.subject | SAFETY | - |
dc.title | Incidence and Risk Factors for Macular Hemorrhage Following Intravitreal Ranibizumab Injection for Neovascular Age-Related Macular Degeneration | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, Jaeryung | - |
dc.identifier.doi | 10.1089/jop.2012.0148 | - |
dc.identifier.scopusid | 2-s2.0-84880200482 | - |
dc.identifier.wosid | 000321616400008 | - |
dc.identifier.bibliographicCitation | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, v.29, no.6, pp.556 - 559 | - |
dc.relation.isPartOf | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS | - |
dc.citation.title | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS | - |
dc.citation.volume | 29 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 556 | - |
dc.citation.endPage | 559 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | COMPLICATIONS | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | SAFETY | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.