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Chronic Obstructive Pulmonary Disease Assessment Test Can Predict Depression: A Prospective Multi-Center Study

Authors
Lee, Young SeokPark, SunghoonOh, Yeon-MokLee, Sang-DoPark, Sung-WooKim, Young SamIn, Kwang HoJung, Bock HyunLee, Kwan HoRa, Seung WonHwang, Yong IlPark, Yong-BumJung, Ki-Suck
Issue Date
7월-2013
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Pulmonary Disease, Chronic Obstructive; COPD Assessment Test; Depression
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.28, no.7, pp.1048 - 1054
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
28
Number
7
Start Page
1048
End Page
1054
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/102903
DOI
10.3346/jkms.2013.28.7.1048
ISSN
1011-8934
Abstract
This study was conducted to investigate the association between the chronic obstructive pulmonary disease (COPD) assessment test (CAT) and depression in COPD patients. The Korean versions of the CAT and patient health questionnaire-9 (PHQ-9) were used to assess COPD symptoms and depressive disorder, respectively. In total, 803 patients with COPD were enrolled from 32 hospitals and the prevalence of depression was 23.8%. The CAT score correlated well with the PHQ-9 score (r=0.631; P<0.001) and was significantly associated with the presence of depression (beta +/- standard error, 0.452 +/- 0.020; P<0.001). There was a tendency toward increasing severity of depression in patients with higher CAT scores. By assessment groups based on the 2011 Global Initiative for Chronic Obstructive Lung Disease guidelines, the prevalence of depression was affected more by current symptoms than by airway limitation. The area under the receiver operating characteristic curve for the CAT was 0.849 for predicting depression, and CAT scores >= 21 had the highest accuracy rate (80.6%). Among the eight CAT items, energy score showed the best correlation and highest power of discrimination. CAT scores are significantly associated with the presence of depression and have good performance for predicting depression in COPD patients.
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