Case-Control Study of the Effectiveness of the 2010-2011 Seasonal Influenza Vaccine for Prevention of Laboratory-Confirmed Influenza Virus Infection in the Korean Adult Population
- Authors
- Choi, Won Suk; Noh, Ji Yun; Seo, Yu Bin; Baek, Ji Hyeon; Lee, Jacob; Song, Joon Young; Park, Dae Won; Lee, Jin Soo; Cheong, Hee Jin; Kim, Woo Joo
- Issue Date
- Jun-2013
- Publisher
- AMER SOC MICROBIOLOGY
- Citation
- CLINICAL AND VACCINE IMMUNOLOGY, v.20, no.6, pp.877 - 881
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL AND VACCINE IMMUNOLOGY
- Volume
- 20
- Number
- 6
- Start Page
- 877
- End Page
- 881
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/103163
- DOI
- 10.1128/CVI.00009-13
- ISSN
- 1556-6811
- Abstract
- We evaluated the effectiveness of the 2010-2011 seasonal influenza vaccine for preventing laboratory-confirmed influenza in a South Korean population. A retrospective case-control study was conducted among patients who visited selected hospitals from September 2010 to May 2011. A total of 483 laboratory-confirmed influenza patients were included in the analysis as case subjects. For each case patient, two types of control patients were chosen at a ratio of 1:1:1, and 966 control subjects were selected. Vaccine effectiveness (VE) was defined as 100 x (1 - odds ratio for influenza in vaccinated versus nonvaccinated persons). The VE of the 2010-2011 seasonal influenza vaccine was 49.5% to 45.8% for both influenza A and B viruses and 50.8% to 47.2% for influenza A virus, according to the control type. The age-specific adjusted VE was 50.8% to 46.5% among subjects aged 19 to 49 years and 58.7% to 63.3% among those aged 50 to 64 years, according to the control type. Statistically significant VE was not found among those aged >= 65 years or against influenza B virus. The 2010-2011 seasonal influenza vaccine was effective for preventing laboratory-confirmed influenza, especially for influenza A virus, in a South Korean population. Evidence of the effectiveness of the influenza vaccine in older adults or against influenza B virus was not found.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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