The interrelationship between non-motor symptoms in Atypical Parkinsonism
DC Field | Value | Language |
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dc.contributor.author | Lee, Chan-Nyoung | - |
dc.contributor.author | Kim, Minjik | - |
dc.contributor.author | Lee, Hye Mi | - |
dc.contributor.author | Jang, Ji-Wan | - |
dc.contributor.author | Lee, Seon-Min | - |
dc.contributor.author | Kwon, Do-Young | - |
dc.contributor.author | Park, Kun-Woo | - |
dc.contributor.author | Koh, Seong-Beom | - |
dc.date.accessioned | 2021-09-06T02:35:43Z | - |
dc.date.available | 2021-09-06T02:35:43Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-04-15 | - |
dc.identifier.issn | 0022-510X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103502 | - |
dc.description.abstract | Background: Atypical Parkinsonism is less common and has more severe symptoms than Parkinson's disease (PD). Little is known about the non-motor symptom (NMS) characteristics of multiple systemic atrophy (MSA) or progressive supranuclear palsy (PSP). We report the interrelationship of NMS in MSA, PSP, and PD. Methods: We studied 117 cases of PD and 57 of Atypical Parkinsonism. Out of the 57 patients, 31 had multiple systemic atrophy parkinsonian subtype (MSA-P), 14 had multiple systemic atrophy cerebellar dysfunction subtype (MSA-C), and 12 had PSP. We assessed the condition of the patients using the United Parkinson's Disease Rating Scale part III (UPDRS-III), the modified Hoehn & Yahr scale (H&Y), the non-motor symptom scale (NMSS), and the Parkinson's Disease Questionnaire (PDQ-39). Results: In Atypical Parkinsonism, the NMSS scores significantly correlated with PDQ-39 scores, but not with UPDRS-III. In the MSA-P group, the mood/cognitive domain significantly correlated with both the urinary and sleep/fatigue domains. In the MSA-C group, the sleep/fatigue domain correlated with the mood/cognition and cardiovascular domains. Finally, in the PSP and PD groups, the attention/memory domain significantly correlated with the sleep/fatigue and mood/cognition domains. Discussion: These results suggest that, with respect to cognitive function, dysautonomia and sleep/fatigue are detrimental factors in MSA and PSP, respectively. (c) 2013 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | MULTIPLE SYSTEM ATROPHY | - |
dc.subject | PROGRESSIVE SUPRANUCLEAR PALSY | - |
dc.subject | SYMPATHETIC SKIN-RESPONSE | - |
dc.subject | QUALITY-OF-LIFE | - |
dc.subject | DAYTIME SLEEPINESS | - |
dc.subject | DISEASE | - |
dc.subject | DIAGNOSIS | - |
dc.subject | DISORDER | - |
dc.subject | SCALE | - |
dc.title | The interrelationship between non-motor symptoms in Atypical Parkinsonism | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kwon, Do-Young | - |
dc.contributor.affiliatedAuthor | Park, Kun-Woo | - |
dc.contributor.affiliatedAuthor | Koh, Seong-Beom | - |
dc.identifier.doi | 10.1016/j.jns.2013.01.034 | - |
dc.identifier.scopusid | 2-s2.0-84875216628 | - |
dc.identifier.wosid | 000317552600004 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE NEUROLOGICAL SCIENCES, v.327, no.1-2, pp.15 - 21 | - |
dc.relation.isPartOf | JOURNAL OF THE NEUROLOGICAL SCIENCES | - |
dc.citation.title | JOURNAL OF THE NEUROLOGICAL SCIENCES | - |
dc.citation.volume | 327 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 15 | - |
dc.citation.endPage | 21 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | MULTIPLE SYSTEM ATROPHY | - |
dc.subject.keywordPlus | PROGRESSIVE SUPRANUCLEAR PALSY | - |
dc.subject.keywordPlus | SYMPATHETIC SKIN-RESPONSE | - |
dc.subject.keywordPlus | QUALITY-OF-LIFE | - |
dc.subject.keywordPlus | DAYTIME SLEEPINESS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | DISORDER | - |
dc.subject.keywordPlus | SCALE | - |
dc.subject.keywordAuthor | Parkinson&apos | - |
dc.subject.keywordAuthor | s disease | - |
dc.subject.keywordAuthor | Multiple system atrophy | - |
dc.subject.keywordAuthor | Progressive supranuclear palsy | - |
dc.subject.keywordAuthor | Non-motor symptoms | - |
dc.subject.keywordAuthor | Quality of life | - |
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