Multicenter Analysis of Risk Factors for Anastomotic Leakage After Laparoscopic Rectal Cancer Excision The Korean Laparoscopic Colorectal Surgery Study Group
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jun Seok | - |
dc.contributor.author | Choi, Gyu-Seog | - |
dc.contributor.author | Kim, Seon Hahn | - |
dc.contributor.author | Kim, Hyeong Rok | - |
dc.contributor.author | Kim, Nam Kyu | - |
dc.contributor.author | Lee, Kang Young | - |
dc.contributor.author | Kang, Sung Bum | - |
dc.contributor.author | Kim, Ji Yeon | - |
dc.contributor.author | Lee, Kil Yeon | - |
dc.contributor.author | Kim, Byung Chun | - |
dc.contributor.author | Bae, Byung Noe | - |
dc.contributor.author | Son, Gyung Mo | - |
dc.contributor.author | Lee, Sun Il. | - |
dc.contributor.author | Kang, Hyun | - |
dc.date.accessioned | 2021-09-06T02:56:37Z | - |
dc.date.available | 2021-09-06T02:56:37Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013-04 | - |
dc.identifier.issn | 0003-4932 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/103610 | - |
dc.description.abstract | Objective: To assess the risk factors for clinical anastomotic leakage (AL) in patients undergoing laparoscopic surgery for rectal cancer. Background: Little data are available about risk factors for AL after laparoscopic rectal cancer resection. Methods: This was a retrospective analysis of 1609 patients with rectal cancer who had undergone laparoscopic surgery for rectal cancer with sphincter preservation. Clinical data related to AL were collected from 11 institutions. Univariate and multivariate analyses were performed to determine the risk factors for AL. Results: AL was noted in 101 (6.3%) of the patients. The leakage rate ranged from 2.0% to 10.3% for each hospital (P = 0.04). In patients without protective stomas (n = 1187), male sex [hazard ratio (HR), 3.468], advanced tumor stage (HR, 2.520), lower tumor level (HR, 2.418), preoperative chemoradiation (HR, 6.284), perioperative transfusion (HR, 10.705), and multiple firings of the linear stapler (HR, 6.181) were significantly associated with AL. Our theoretical model suggested that the HR for patients with 2 risk factors was significantly higher than that the HR for patients with no or only 1 risk factor. Conclusions: Male sex, low anastomosis, preoperative chemoradiation, advanced tumor stage, perioperative bleeding, and multiple firings of the linear stapler increased the risk of AL after laparoscopic surgery for rectal cancer. A diverting stoma might be mandatory in patients with 2 or more of the risk factors identified in this analysis. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | LOW ANTERIOR RESECTION | - |
dc.subject | TOTAL MESORECTAL EXCISION | - |
dc.subject | SHORT-TERM OUTCOMES | - |
dc.subject | DEFUNCTIONING STOMA | - |
dc.subject | RANDOMIZED-TRIAL | - |
dc.subject | PREOPERATIVE RADIOTHERAPY | - |
dc.subject | CARCINOMA | - |
dc.subject | EXTRAPERITONEAL | - |
dc.subject | METAANALYSIS | - |
dc.subject | SURVIVAL | - |
dc.title | Multicenter Analysis of Risk Factors for Anastomotic Leakage After Laparoscopic Rectal Cancer Excision The Korean Laparoscopic Colorectal Surgery Study Group | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Seon Hahn | - |
dc.contributor.affiliatedAuthor | Lee, Sun Il. | - |
dc.identifier.doi | 10.1097/SLA.0b013e31827b8ed9 | - |
dc.identifier.scopusid | 2-s2.0-84875227738 | - |
dc.identifier.wosid | 000315990100021 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGERY, v.257, no.4, pp.665 - 671 | - |
dc.relation.isPartOf | ANNALS OF SURGERY | - |
dc.citation.title | ANNALS OF SURGERY | - |
dc.citation.volume | 257 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 665 | - |
dc.citation.endPage | 671 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | LOW ANTERIOR RESECTION | - |
dc.subject.keywordPlus | TOTAL MESORECTAL EXCISION | - |
dc.subject.keywordPlus | SHORT-TERM OUTCOMES | - |
dc.subject.keywordPlus | DEFUNCTIONING STOMA | - |
dc.subject.keywordPlus | RANDOMIZED-TRIAL | - |
dc.subject.keywordPlus | PREOPERATIVE RADIOTHERAPY | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | EXTRAPERITONEAL | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordAuthor | anastomotic leakage | - |
dc.subject.keywordAuthor | laparoscopic surgery | - |
dc.subject.keywordAuthor | rectal cancer | - |
dc.subject.keywordAuthor | risk factor | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.