Long-acting Injectable Antipsychotics in First-episode Schizophrenia
- Authors
- Jeong, Hyun Ghang; Lee, Moon Soo
- Issue Date
- 4월-2013
- Publisher
- KOREAN COLL NEUROPSYCHOPHARMACOLOGY
- Keywords
- Antipsychotic agents; Injections; Schizophrenia; Delayed-action preparations
- Citation
- CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, v.11, no.1, pp.1 - 6
- Indexed
- SCOPUS
KCI
OTHER
- Journal Title
- CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
- Volume
- 11
- Number
- 1
- Start Page
- 1
- End Page
- 6
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/103680
- DOI
- 10.9758/cpn.2013.11.1.1
- ISSN
- 1738-1088
- Abstract
- Antipsychotic medications are important for the successful management of schizophrenia. Continuous treatment with medication is superior in relapse prevention and non-adherence to antipsychotic medication is associated with a poor clinical outcome. Long-acting injectable antipsychotics (LAIs) that can guarantee adherence to a treatment regimen could be a useful treatment option. With the introduction of second-generation atypical antipsychotics-long acting injection (SGA-LAI), the risks for ex trapyramidal adverse events are decreased. The indications for SGA-LAI have been extended from chronic, stabilized patients to acute psychotic patients. Some studies investigated the use of LAI in first-episode schizophrenia patients and raised the possibility of prescribing LAI as a treatment option. However, there is still limited research using LAI in first-episode schizophrenia. More well designed, randomized, controlled clinical trials using SGA-LAIs in first-episode schizophrenia are needed, Additionally, studies on side effects of SGA-LAI in long-term use are required prior to recommending LAI for patients with first episode schizophrenia.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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