Enzyme stabilization by nano/microsized hybrid materials
- Authors
- Hwang, Ee Taek; Gu, Man Bock
- Issue Date
- 1월-2013
- Publisher
- WILEY
- Keywords
- Enzyme stabilization; Enzyme immobilization; Hybrid materials; Nanomaterials; Type of enzyme immobilization
- Citation
- ENGINEERING IN LIFE SCIENCES, v.13, no.1, pp.49 - 61
- Indexed
- SCIE
SCOPUS
- Journal Title
- ENGINEERING IN LIFE SCIENCES
- Volume
- 13
- Number
- 1
- Start Page
- 49
- End Page
- 61
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/104255
- DOI
- 10.1002/elsc.201100225
- ISSN
- 1618-0240
- Abstract
- Immobilization is a key technology for successful realization of enzyme-based industrial processes, particularly for production of green and sustainable energy or chemicals from biomass-derived catalytic conversion. Different methods to immobilize enzymes are critically reviewed. In principle, enzymes are immobilized via three major routes (i) binding to a support, (ii) encapsulation or entrapment, or (iii) cross-linking (carrier free). As a result, immobilizing enzymes on certain supports can enhance storage and operational stability. In addition, recent breakthroughs in nano and hybrid technology have made various materials more affordable hosts for enzyme immobilization. This review discusses different approaches to improve enzyme stability in various materials such as nanoparticles, nanofibers, mesoporous materials, solgel silica, and alginate-based microspheres. The advantages of stabilized enzyme systems are from its simple separation and ease recovery for reuse, while maintaining activity and selectivity. This review also considers the latest studies conducted on different enzymes immobilized on various support materials with immense potential for biosensor, antibiotic production, food industry, biodiesel production, and bioremediation, because stabilized enzyme systems are expected to be environmental friendly, inexpensive, and easy to use for enzyme-based industrial applications.
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Collections - Graduate School > Department of Biotechnology > 1. Journal Articles
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