Impact of insulin resistance on 1-year clinical outcomes in non-diabetic patients undergoing percutaneous coronary intervention with drug-eluting stents
- Authors
- Hwang, In Kyeom; Kim, Yun Kyung; Rha, Seung-Woon; Ra, Ji Eun; Seo, Bong Soo; Lee, Ji Kyoung; Na, Jin Oh; Choi, Cheol Ung; Lim, Hong Euy; Han, Seong Woo; Kim, Eung Ju; Park, Chang Gyu; Seo, Hong Seog; Oh, Dong Joo; Choi, Sang Myung; Chae, Byoung Gy; Kim, Sung-Jin; Yoon, Seong Gyu; Suh, Il Woo
- Issue Date
- 1월-2013
- Publisher
- ELSEVIER IRELAND LTD
- Keywords
- Insulin resistance; Drug-eluting stent
- Citation
- JOURNAL OF CARDIOLOGY, v.61, no.1-2, pp.113 - 116
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CARDIOLOGY
- Volume
- 61
- Number
- 1-2
- Start Page
- 113
- End Page
- 116
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/104322
- DOI
- 10.1016/j.jjcc.2012.08.022
- ISSN
- 0914-5087
- Abstract
- Background: Insulin resistance (IR) is known to be a risk factor for coronary artery disease (CAD). We aimed to evaluate the impact of IR on 1-year clinical outcomes in non-diabetic CAD patients who underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DESs). Methods and results: A total of 229 consecutive non-diabetic CAD patients treated with DESs were enrolled. Study population was divided into IR group [homeostasis model assessment (HOMA) index >= 2.5, n = 54] and non-IR group (HOMA index < 2.5, n =175). Baseline clinical and procedural characteristics were similar between the groups except higher incidence of high-sensitivity C-reactive protein and lower incidence of multivessel disease as the target vessel in the non-IR group. There was a trend toward longer restenosis lesion length in the IR group at 6 months angiographic follow up but composite major clinical outcomes up to 1 year were similar between the two groups. Conclusions: Despite worse trend in angiographic outcomes in the IR group (HOMA index >= 2.5), it was not translated into worse 1-year major clinical outcomes following PCI with DESs as compared to the non-IR group. (C) 2012 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
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