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작업장에서의 n-부틸 글리시딜 에테르에 대한 건강 위험성 평가Human Health Risk Assessment of n-Butyl Glycidyl Ether from Occupational Workplaces

Other Titles
Human Health Risk Assessment of n-Butyl Glycidyl Ether from Occupational Workplaces
Authors
문형일최현일신새미변상훈
Issue Date
2013
Publisher
한국산업보건학회
Keywords
risk assessment; butyl glycidyl ether; workplace reference concentration; NOAEL; monte-carlo simulation
Citation
한국산업보건학회지, v.23, no.1, pp.20 - 26
Indexed
KCI
Journal Title
한국산업보건학회지
Volume
23
Number
1
Start Page
20
End Page
26
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/104945
ISSN
2384-132x
Abstract
Objectives: This study was conducted to evaluate the health risk of workers exposed to butyl glycidyl ether to prevent them from developing occupational diseases. Methods: The workplaces that coat floor with epoxy were selected and the samples were collected and analyzed with NIOSH 1616 Method. We calculate workplace reference concentration using with NOAEL estimated by the study of Anderson et al. in 1978. Risk was calculated by the ratio of exposure to workplace reference concentration. Monte-Carlo simulation was performed to derivate the median, cumulative 90%, and cumulative 95% value by using Crystal Ball. Resultts: Butyl glycidyl ether is a skin, eye irritator and can result in central nervous system depression, allergic reaction. NOAEL was 38 ppm and workplace reference concentration was calculated as 0.73 ppm corrected with uncertainty factors. Geometric mean was 1.152 ppm and geometric standard deviation was 1.522 by the workplace environment measurement. The median, cumulative 90%, and cumulative 95% value of risk were calculated as 1.617, 1.934, and 2.092, respectively. Conclusions: Not only cumulative 90% and cumulative 95% value but also the median of risk is higher than 1.0 by the risk characterization, so it can do a lot of harm to workers. Therefore, the process of derivating workplace reference concentration and the appropriacy of the uncertainty factors should be re-examined.
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보건과학대학 (보건환경융합과학부)
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