Case of disseminated vesicles of herpes zoster developing one day before the onset of local eruption in a hospitalized immunocompromised patient
- Authors
- Mabuchi, T.; Yamaoka, H.; Kato, M.; Ikoma, N.; Tamiya, S.; Song, H.-J.; Nakamura, N.; Ozawa, A.
- Issue Date
- 2013
- Keywords
- Disseminated herpes zoster; Generalized herpes zoster; Recurrence; Reinfection; VZV-specific memory T cells
- Citation
- Tokai Journal of Experimental and Clinical Medicine, v.38, no.2, pp.52 - 54
- Indexed
- SCOPUS
- Journal Title
- Tokai Journal of Experimental and Clinical Medicine
- Volume
- 38
- Number
- 2
- Start Page
- 52
- End Page
- 54
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/105884
- ISSN
- 0385-0005
- Abstract
- Disseminated herpes zoster is not rare in immunocompromised patient. It is defined as at least 20 lesions in multiple dermatomes that occur within a week of the onset of local eruption. Herein, we report that a case of disseminated vesicles of herpes zoster (HZ) that developed one day before the onset of local eruption in an immunocompromised patient. A 44 year-old Japanese male, who had been in the hospital with acute myelocytic leukemia, developed disseminated hemorrhagic vesicles of 5 to 10 mm in diameter. The next day, grouped vesicles, including hemorrhagic vesicles erupted on the right side of the second to third cervical (C2-C3) dermatomes. At this point, the diagnosis was made as disseminated herpes zoster. The activation of varicella-zoster virus (VZV) is believed to be due to waning of VZV-specific memory T cell responses. In our case, the memory immunity to VZV which had been increased by last episode of HZ might affect on the appearance of skin eruptions.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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