Corynebacterium glutamicum whcB, a stationary phase-specific regulatory gene
DC Field | Value | Language |
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dc.contributor.author | Lee, Joo-Young | - |
dc.contributor.author | Park, Joon-Song | - |
dc.contributor.author | Kim, Hyung-Joon | - |
dc.contributor.author | Kim, Younhee | - |
dc.contributor.author | Lee, Heung-Shick | - |
dc.date.accessioned | 2021-09-06T10:42:07Z | - |
dc.date.available | 2021-09-06T10:42:07Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2012-02 | - |
dc.identifier.issn | 0378-1097 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/106210 | - |
dc.description.abstract | The function of whcB, one of the four whiB homologues of Corynebacterium glutamicum, was assessed. Cells carrying the P180-whcB clone, and thus overexpressing the whcB gene, showed retarded growth, probably due to increased sensitivity to oxidants, whereas cells lacking whcB (?whcB) did not. However, growth retardation was not observed in cells with additionally whcE deleted. Furthermore, the ?whcE phenotype, characterized by slow growth and sensitivity to oxidants, was reversed in cells carrying P180-whcB. Like the whcE gene, which is also known as a whiB homologue, the whcB gene was preferentially expressed in stationary phase. Determination of the genes under regulation of whcB using two-dimensional polyacrylamide gel electrophoresis identified several genes involved in electron transfer reactions that were regulated in cells carrying P180-whcB. Collectively, these findings indicate that whcB function requires whcE. Furthermore, whcB and whcE are paralogues but perform distinct regulatory roles during growth under oxidative stress. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | 4FE-4S CLUSTER | - |
dc.subject | NITRIC-OXIDE | - |
dc.subject | STREPTOMYCES | - |
dc.subject | WHIB | - |
dc.subject | PROTEIN | - |
dc.subject | SPORULATION | - |
dc.subject | EXPRESSION | - |
dc.subject | SEQUENCE | - |
dc.subject | HOMOLOG | - |
dc.title | Corynebacterium glutamicum whcB, a stationary phase-specific regulatory gene | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Heung-Shick | - |
dc.identifier.doi | 10.1111/j.1574-6968.2011.02463.x | - |
dc.identifier.scopusid | 2-s2.0-84855783736 | - |
dc.identifier.wosid | 000298987000003 | - |
dc.identifier.bibliographicCitation | FEMS MICROBIOLOGY LETTERS, v.327, no.2, pp.103 - 109 | - |
dc.relation.isPartOf | FEMS MICROBIOLOGY LETTERS | - |
dc.citation.title | FEMS MICROBIOLOGY LETTERS | - |
dc.citation.volume | 327 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 103 | - |
dc.citation.endPage | 109 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | 4FE-4S CLUSTER | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | STREPTOMYCES | - |
dc.subject.keywordPlus | WHIB | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | SPORULATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | SEQUENCE | - |
dc.subject.keywordPlus | HOMOLOG | - |
dc.subject.keywordAuthor | Corynebacterium glutamicum | - |
dc.subject.keywordAuthor | whcB | - |
dc.subject.keywordAuthor | whcE | - |
dc.subject.keywordAuthor | oxidative stress | - |
dc.subject.keywordAuthor | whiB | - |
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