Magnetic nanocomplexes and the physiological challenges associated with their use for cancer imaging and therapy
- Authors
- Kim, Eunjung; Lee, Kwangyeol; Huh, Yong-Min; Haam, Seungjoo
- Issue Date
- 2013
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- JOURNAL OF MATERIALS CHEMISTRY B, v.1, no.6, pp.729 - 739
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF MATERIALS CHEMISTRY B
- Volume
- 1
- Number
- 6
- Start Page
- 729
- End Page
- 739
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/106401
- DOI
- 10.1039/c2tb00294a
- ISSN
- 2050-7518
- Abstract
- Magnetic nanoparticles offer potential advances in cancer treatment. One example is cancer theranostics, which refers to the combination of a diagnostic tool, i.e., magnetic resonance (MR) imaging, and therapeutic entities such as drugs, oligonucleotides, antibodies, and peptides. They can be conjugated with bioactive molecules and have the ability to form a magnetic field gradient under an external magnetic field. They can offer a variety of active drug delivery and imaging strategies along with modalities such as magnetic hyperthermia. Imaging with magnetic nanoparticles can facilitate more effective cancer therapy through more well informed decision-making. In this article, we review notable progress in magnetic particle design, including surface modifications and multi-functionalization, and we discuss the recent bioapplications of magnetic nanoparticles in simultaneous cancer imaging and therapy.
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- Appears in
Collections - College of Science > Department of Chemistry > 1. Journal Articles
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