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Do We Need to Consider Ethno-cultural Variation in the Use of Atypical Antipsychotics for Asian Patients with Major Depressive Disorder?

Authors
Han, ChangsuPae, Chi-Un
Issue Date
2013
Publisher
ADIS INT LTD
Citation
CNS DRUGS, v.27, pp.S47 - S51
Indexed
SCIE
SCOPUS
Journal Title
CNS DRUGS
Volume
27
Start Page
S47
End Page
S51
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/106402
DOI
10.1007/s40263-012-0033-y
ISSN
1172-7047
Abstract
Asian and western countries differ in the prevalence, symptom manifestation, diagnostic procedures, patient recognition and treatments of major depressive disorder (MDD), according to a number of studies. Ethnic differences in pharmacological profiles are also important in the prescription of certain antipsychotic medications because they may impact treatment outcomes and adverse events. Differential pharmacokinetic and pharmacodynamic properties of antipsychotics may be practically useful in the control of specific depressive symptoms. Furthermore, patient compliance with prescribed medications has been found to be different across races and ethnicities. Therefore, this article explores practical clinical issues for the use of atypical antipsychotics in patients with MDD, focusing on ethno-cultural differences.
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의과대학 (의학과)
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