Associations between vascular endothelial growth factor gene polymorphisms and pre-eclampsia susceptibility: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Song, Gwan Gyu | - |
dc.contributor.author | Kim, Jae-Hoon | - |
dc.contributor.author | Lee, Young Ho | - |
dc.date.accessioned | 2021-09-06T11:12:55Z | - |
dc.date.available | 2021-09-06T11:12:55Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0882-0139 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/106416 | - |
dc.description.abstract | Objective: The aim of this study was to assess whether vascular endothelial growth factor (VEGF) polymorphisms are associated with susceptibility to pre-eclampsia. Methods: A meta-analysis was conducted on the associations between the -634 C/G, +936 C/T, -1154 A/G, and -2578 A/C polymorphisms of VEGF and pre-eclampsia. Results: Ten studies involving 2068 subjects (pre-eclampsia, 950; controls, 1118) were included in the meta-analysis. The meta-analysis revealed an association between pre-eclampsia and the VEGF -634C allele in overall group (OR = 1.351, 95% CI = 1.105-1.651, p = 0.003) and in European group (OR = 1.427, 95% CI = 1.139-1.787, p = 0.002). The meta-analysis revealed an association between pre-eclampsia and the VEGF -936T allele in Asians, but not in Europeans (OR = 1.555, 95% CI = 1.232-1.961, p = 1.9 x 10(-5); OR -1.587, 95% CI -0.933-2.699, p = 0.088). However, the meta-analysis revealed no association between pre-eclampsia and the VEGF -1154 A/G and 2578 A/C polymorphisms Conclusions: This meta-analysis suggested that the VEGF -634 C/G polymorphism is associated with susceptibility to pre-eclampsia in Europeans and that the VEGF -634 C/G polymorphism is associated with pre-eclampsia in Asians. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS INC | - |
dc.subject | FACTOR VEGF | - |
dc.subject | NITRIC-OXIDE | - |
dc.subject | DIMETHYLARGININE | - |
dc.subject | CELLS | - |
dc.title | Associations between vascular endothelial growth factor gene polymorphisms and pre-eclampsia susceptibility: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Gwan Gyu | - |
dc.contributor.affiliatedAuthor | Kim, Jae-Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Young Ho | - |
dc.identifier.doi | 10.3109/08820139.2013.822394 | - |
dc.identifier.scopusid | 2-s2.0-84885461532 | - |
dc.identifier.wosid | 000325402800007 | - |
dc.identifier.bibliographicCitation | IMMUNOLOGICAL INVESTIGATIONS, v.42, no.8, pp.749 - 762 | - |
dc.relation.isPartOf | IMMUNOLOGICAL INVESTIGATIONS | - |
dc.citation.title | IMMUNOLOGICAL INVESTIGATIONS | - |
dc.citation.volume | 42 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 749 | - |
dc.citation.endPage | 762 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | FACTOR VEGF | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | DIMETHYLARGININE | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordAuthor | Meta-analysis | - |
dc.subject.keywordAuthor | pre-eclampsia | - |
dc.subject.keywordAuthor | polymorphism | - |
dc.subject.keywordAuthor | VEGF | - |
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