Efficacy of systematic pelvic lymphadenectomy in patients with non-endometrioid endometrial cancers: A retrospective, multicenter study in Korea
- Authors
- Tong, Seo-Yun; Lee, Jong-Min; Choi, Young-Joon; Lee, Jae-Kwan; Kim, Mi-Kyung; Cho, Chi-Heum; Kim, Seok-Mo; Park, Sang-Yoon; Park, Chan-Yong; Kim, Ki-Tae
- Issue Date
- 11월-2012
- Publisher
- WILEY-BLACKWELL
- Keywords
- endometrial neoplasm; lymphadenectomy; non-endometrioid; prognosis
- Citation
- JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, v.38, no.11, pp.1321 - 1327
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
- Volume
- 38
- Number
- 11
- Start Page
- 1321
- End Page
- 1327
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/106986
- DOI
- 10.1111/j.1447-0756.2012.01875.x
- ISSN
- 1341-8076
- Abstract
- Aim: Non-endometrioid endometrial cancer is a clinically and pathologically distinct subtype of endometrial cancer. The aim of this study was to determine whether systematic pelvic lymphadenectomy improves overall survival compared to no lymphadenectomy in non-endometrioid endometrial cancer. Material and Methods: The authors retrospectively reviewed the medical records and pathological findings of 112 patients who underwent surgical staging for non-endometrioid endometrial cancer from 2000 to 2006 in Korea. Results: Systematic pelvic lymphadenectomy was performed in 71 patients. Pelvic lymph node metastases were identified in 31% and 14.6% patients who underwent systematic pelvic lymphadenectomy and no lymphadenectomy, respectively. After adjusting for risk factors, there was no significant difference in overall survival (odds ratio = 0.69; 95% confidence interval, 0.29-1.67) between patients who did or did not undergo systematic pelvic lymphadenectomy. On multivariate analysis, patients with lymph node metastasis had higher risk of death (odds ratio = 3.11; 95% confidence interval, 0.97-10.00) than the patients with no lymph node metastasis. Conclusion: Although systematic pelvic lymphadenectomy did not affect overall survival in patients with the non-endometrioid subtype, it has the potential benefit of providing prognostic information and acting as a guide for further adjuvant treatment.
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