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Dual-Color Imaging of Magnesium/Calcium Ion Activities with Two-Photon Fluorescent Probes
- Issue Date
- 2-10월-2012
- Publisher
- AMER CHEMICAL SOC
- Citation
- ANALYTICAL CHEMISTRY, v.84, no.19, pp.8110 - 8113
- Indexed
- SCIE
SCOPUS
- Journal Title
- ANALYTICAL CHEMISTRY
- Volume
- 84
- Number
- 19
- Start Page
- 8110
- End Page
- 8113
- ISSN
- 0003-2700
- Abstract
- We report two-photon probes (FMg1 and FMg2) that can selectively detect intracellular free Mg2+ ([Mg2+](i)) in live cells and tissues by two-photon microscopy. Combined with BCaM, a two-photon probe for near-membrane Ca2+ ([Ca2+](m)), FMg2 allows dual-color imaging of Mg2+/Ca2+ activities in live cells and [Mg2+](i)/[Ca2+](m) distributions in live tissues at a depth of 100-200 mu m.
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Collections - College of Science > Department of Chemistry > 1. Journal Articles
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