How low is low enough? Evaluation of various risk-assessment models for lymph node metastasis in endometrial cancer: a Korean multicenter study
DC Field | Value | Language |
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dc.contributor.author | Kang, Sokbom | - |
dc.contributor.author | Lee, Jong-Min | - |
dc.contributor.author | Lee, Jae-Kwan | - |
dc.contributor.author | Kim, Jae Weon | - |
dc.contributor.author | Cho, Chi-Heum | - |
dc.contributor.author | Kim, Seok-Mo | - |
dc.contributor.author | Park, Sang-Yoon | - |
dc.contributor.author | Park, Chan-Yong | - |
dc.contributor.author | Kim, Ki-Tae | - |
dc.date.accessioned | 2021-09-06T14:43:32Z | - |
dc.date.available | 2021-09-06T14:43:32Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 2005-0380 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/107240 | - |
dc.description.abstract | Objective: The aim of this study was to identify a standard for the evaluation of future models for prediction of lymph node metastasis in endometrial cancer through estimation of performance of well-known surgicopathological models. Methods: Using the medical records of 947 patients with endometrial cancer who underwent surgical management with lymphadenectomy, we retrospectively assessed the predictive performances of nodal metastasis of currently available models. Results: We evaluated three models included: 1) a model modified from the Gynecologic Oncology Group (GOG) pilot study; 2) one from the GOG-33 data; and 3) one from Mayo Clinic data. The three models showed similar negative predictive values ranging from 97.1% to 97.4%. Using Bayes' theorem, this can be translated into 2% of negative post-test probability when 10% of prevalence of lymph node metastasis was assumed. In addition, although the negative predictive value was similar among these models, the proportion that was classified as low-risk was significantly different between the studies (56.4%, 44.8%, and 30.5%, respectively; p<0.001). Conclusion: The current study suggests that a false negativity of 2% or less should be a goal for determining clinical usefulness of preoperative or intraoperative prediction models for low-risk of nodal metastasis. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC GYNECOLOGY ONCOLOGY & COLPOSCOPY | - |
dc.subject | GYNECOLOGIC-ONCOLOGY-GROUP | - |
dc.subject | SYSTEMATIC PELVIC LYMPHADENECTOMY | - |
dc.subject | RANDOMIZED CLINICAL-TRIAL | - |
dc.subject | UTERINE-CANCER | - |
dc.subject | DIAGNOSTIC-ACCURACY | - |
dc.subject | MEDICAL LITERATURE | - |
dc.subject | USERS GUIDES | - |
dc.subject | STAGE | - |
dc.subject | CARCINOMA | - |
dc.subject | MANAGEMENT | - |
dc.title | How low is low enough? Evaluation of various risk-assessment models for lymph node metastasis in endometrial cancer: a Korean multicenter study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Jae-Kwan | - |
dc.identifier.doi | 10.3802/jgo.2012.23.4.251 | - |
dc.identifier.scopusid | 2-s2.0-84867182268 | - |
dc.identifier.wosid | 000309041200007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GYNECOLOGIC ONCOLOGY, v.23, no.4, pp.251 - 256 | - |
dc.relation.isPartOf | JOURNAL OF GYNECOLOGIC ONCOLOGY | - |
dc.citation.title | JOURNAL OF GYNECOLOGIC ONCOLOGY | - |
dc.citation.volume | 23 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 251 | - |
dc.citation.endPage | 256 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001704154 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.subject.keywordPlus | GYNECOLOGIC-ONCOLOGY-GROUP | - |
dc.subject.keywordPlus | SYSTEMATIC PELVIC LYMPHADENECTOMY | - |
dc.subject.keywordPlus | RANDOMIZED CLINICAL-TRIAL | - |
dc.subject.keywordPlus | UTERINE-CANCER | - |
dc.subject.keywordPlus | DIAGNOSTIC-ACCURACY | - |
dc.subject.keywordPlus | MEDICAL LITERATURE | - |
dc.subject.keywordPlus | USERS GUIDES | - |
dc.subject.keywordPlus | STAGE | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordAuthor | Endometrial cancer | - |
dc.subject.keywordAuthor | Low-risk group | - |
dc.subject.keywordAuthor | Lymph node dissection | - |
dc.subject.keywordAuthor | Lymphadenectomy | - |
dc.subject.keywordAuthor | Prediction | - |
dc.subject.keywordAuthor | Sensitivity and specificity | - |
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