Associations between eNOS polymorphisms and susceptibility to Behcet's disease: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Lee, Y. H. | - |
dc.contributor.author | Song, G. G. | - |
dc.date.accessioned | 2021-09-06T15:00:25Z | - |
dc.date.available | 2021-09-06T15:00:25Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 0926-9959 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/107338 | - |
dc.description.abstract | Objective To determine whether endothelial nitric oxide synthase (eNOS) polymorphisms confer susceptibility to Behcets disease (BD). Methods A meta-analysis was conducted on the associations between the G894T and 4b/a polymorphisms of eNOS and BD using: (i) the allele contrast, (ii) the recessive model, (iii) the dominant model and (iv) the additive model. Results A total of eight studies, which included 841 cases and 866 controls, were included in the meta-analysis. Meta-analysis of the G894T polymorphism revealed no association with BD in all study subjects or in Turkish and Asian populations. However, one Tunisian study of the T allele showed a significant association with BD (OR = 0.707, 95% CI = 0.5100.980, P = 0.038), but the OR of the T allele among Tunisians was lower, whereas it was higher in Europeans (OR = 2.129, 95% CI = 1.4073.220, P = 0.0003). Meta-analysis showed no association between BD and the 4b/a polymorphism in all study subjects. Stratification by ethnicity indicated no significant association between the a allele of the 4b/a polymorphism and BD in Turkish and Asian populations. Conclusions This meta-analysis shows that the eNOS G894T and the 4b/a polymorphisms are not associated with BD in the Turkish and Asian populations. These data suggest that the G894T and the 4b/a polymorphisms may not confer susceptibility to BD in the Turkish and Asian populations. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | NITRIC-OXIDE SYNTHASE | - |
dc.subject | GENE POLYMORPHISMS | - |
dc.subject | GLU298ASP | - |
dc.title | Associations between eNOS polymorphisms and susceptibility to Behcet's disease: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Y. H. | - |
dc.contributor.affiliatedAuthor | Song, G. G. | - |
dc.identifier.doi | 10.1111/j.1468-3083.2011.04280.x | - |
dc.identifier.scopusid | 2-s2.0-84866242633 | - |
dc.identifier.wosid | 000308587800012 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, v.26, no.10, pp.1266 - 1271 | - |
dc.relation.isPartOf | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | - |
dc.citation.title | JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | - |
dc.citation.volume | 26 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1266 | - |
dc.citation.endPage | 1271 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | NITRIC-OXIDE SYNTHASE | - |
dc.subject.keywordPlus | GENE POLYMORPHISMS | - |
dc.subject.keywordPlus | GLU298ASP | - |
dc.subject.keywordAuthor | NITRIC-OXIDE SYNTHASE | - |
dc.subject.keywordAuthor | GENE POLYMORPHISMS | - |
dc.subject.keywordAuthor | POPULATION | - |
dc.subject.keywordAuthor | ARTERY | - |
dc.subject.keywordAuthor | GLU298ASP | - |
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