Hypoglycemia is associated with increased worry and lower quality of life among patients with type 2 diabetes treated with oral antihyperglycemic agents in the Asia-Pacific region
DC Field | Value | Language |
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dc.contributor.author | Sheu, Wayne H. -H. | - |
dc.contributor.author | Ji, Li-Nong | - |
dc.contributor.author | Nitiyanant, Wannee | - |
dc.contributor.author | Baik, Sei Hyun | - |
dc.contributor.author | Yin, Donald | - |
dc.contributor.author | Mavros, Panagiotis | - |
dc.contributor.author | Chan, Siew-Pheng | - |
dc.date.accessioned | 2021-09-06T20:28:02Z | - |
dc.date.available | 2021-09-06T20:28:02Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2012-05 | - |
dc.identifier.issn | 0168-8227 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/108574 | - |
dc.description.abstract | Aims: We examined the relationship of hypoglycemic symptoms with health-related quality of life and worry about hypoglycemia among type 2 diabetic patients using oral anti-hyperglycemic agents (AHA) in the Asia-Pacific region. Methods: A total of 2257 type 2 diabetic patients with at least 6 months of oral AHA were enrolled in China, Korea, Malaysia, Thailand, and Taiwan. Quality of life was measured with the EuroQol Visual Analog Scale (EQ-VAS) and EuroQol-5 Dimensions questionnaire (EQ-5D), and worry about hypoglycemia with the worry subscale of the Hypoglycemic Fear Survey-II (HFS). Results: The mean (SD) age was 58.7 (10.2) years and HbA(1c) was 7.5% (1.5). The proportion of patients with an HbA(1c) <6.5% and <7% was 24.9% and 41.8%, respectively. Hypoglycemic symptoms in the prior 6 months were reported by 35.8% of patients. Mean scores on the EQ-VAS and the EQ-5D were significantly lower for patients who had hypoglycemic symptoms compared to those who did not (73.6 vs. 76.9, p < 0.001; 0.88 vs. 0.90, p < 0.0001, respectively), whereas mean score on the HFS was significantly higher (12.5 vs. 6.3, p < 0.001). In multi-variate models, hypoglycemic symptoms were independently associated with scores on the EQ-5D, EQ-VAS, and HFS (all p < 0.01-0.001). Symptom severity was positively associated with fear of hypoglycemia (all p <= 0.001). Conclusion: Hypoglycemic symptoms were associated with reduced quality of life and increased patient worry in patients with type 2 diabetes treated with AHA. (C) 2012 Published by Elsevier Ireland Ltd. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.subject | KONG CHINESE PATIENTS | - |
dc.subject | UTILITY MEASURES | - |
dc.subject | FEAR | - |
dc.subject | EQ-5D | - |
dc.subject | PREVALENCE | - |
dc.subject | MANAGEMENT | - |
dc.subject | PREDICTORS | - |
dc.subject | VALIDITY | - |
dc.subject | EUROQOL | - |
dc.subject | STATE | - |
dc.title | Hypoglycemia is associated with increased worry and lower quality of life among patients with type 2 diabetes treated with oral antihyperglycemic agents in the Asia-Pacific region | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Baik, Sei Hyun | - |
dc.identifier.doi | 10.1016/j.diabres.2011.12.027 | - |
dc.identifier.scopusid | 2-s2.0-84860518968 | - |
dc.identifier.wosid | 000303668000018 | - |
dc.identifier.bibliographicCitation | DIABETES RESEARCH AND CLINICAL PRACTICE, v.96, no.2, pp.141 - 148 | - |
dc.relation.isPartOf | DIABETES RESEARCH AND CLINICAL PRACTICE | - |
dc.citation.title | DIABETES RESEARCH AND CLINICAL PRACTICE | - |
dc.citation.volume | 96 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 141 | - |
dc.citation.endPage | 148 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | KONG CHINESE PATIENTS | - |
dc.subject.keywordPlus | UTILITY MEASURES | - |
dc.subject.keywordPlus | FEAR | - |
dc.subject.keywordPlus | EQ-5D | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | PREDICTORS | - |
dc.subject.keywordPlus | VALIDITY | - |
dc.subject.keywordPlus | EUROQOL | - |
dc.subject.keywordPlus | STATE | - |
dc.subject.keywordAuthor | Hypoglycemia | - |
dc.subject.keywordAuthor | Diabetes | - |
dc.subject.keywordAuthor | Worry | - |
dc.subject.keywordAuthor | Quality of life | - |
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