Toxic effects of titanium dioxide nanoparticles on microbial activity and metabolic flux
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Soohyun | - |
dc.contributor.author | Lee, Soojin | - |
dc.contributor.author | Kim, Borim | - |
dc.contributor.author | Lee, Sunhee | - |
dc.contributor.author | Lee, Juhee | - |
dc.contributor.author | Sim, Sangjun | - |
dc.contributor.author | Gu, Manbock | - |
dc.contributor.author | Yi, Jongheop | - |
dc.contributor.author | Lee, Jinwon | - |
dc.date.accessioned | 2021-09-06T21:48:31Z | - |
dc.date.available | 2021-09-06T21:48:31Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2012-04 | - |
dc.identifier.issn | 1226-8372 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/108849 | - |
dc.description.abstract | The purpose of this research is to estimate and quantify the toxicity of titanium dioxide (TiO2) nanoparticles in microorganisms. Nano-sized particles of TiO2 were more toxic compared to micro-sized particles. Three microorganismal species, Escherichia coli, Bacillus subtilis, and Saccharomyces cerevisiae, were used to test TiO2 antimicrobial effects. E. coli showed the lowest survival rate (36%), while S. cerevisiae showed the highest survival rate (71%). The antimicrobial effect of TiO2 was also dependent on ultraviolet ray wavelength. The survival ratio of E. coli was 40% at a 254 nm wavelength and 80% at 365 nm. To observe the effect of TiO2 on the intracellular metabolism, a metabolic flux analysis and the measurement of in vivo glucose-6-phosphate were performed. G6P concentration in cells exposed to TiO2 increased, and glycolysis flux was also higher than the controls. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | BACTERICIDAL ACTION | - |
dc.subject | TIO2 FILMS | - |
dc.subject | ZNO | - |
dc.subject | AG | - |
dc.title | Toxic effects of titanium dioxide nanoparticles on microbial activity and metabolic flux | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Gu, Manbock | - |
dc.identifier.doi | 10.1007/s12257-010-0251-4 | - |
dc.identifier.scopusid | 2-s2.0-84861048790 | - |
dc.identifier.wosid | 000302366300007 | - |
dc.identifier.bibliographicCitation | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.17, no.2, pp.276 - 282 | - |
dc.relation.isPartOf | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.citation.title | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.citation.volume | 17 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 276 | - |
dc.citation.endPage | 282 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001656518 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | BACTERICIDAL ACTION | - |
dc.subject.keywordPlus | TIO2 FILMS | - |
dc.subject.keywordPlus | ZNO | - |
dc.subject.keywordPlus | AG | - |
dc.subject.keywordAuthor | TiO2 nanoparticles | - |
dc.subject.keywordAuthor | antimicrobial activity | - |
dc.subject.keywordAuthor | metabolic flux analysis | - |
dc.subject.keywordAuthor | glucose-6-phosphate | - |
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