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Multi-core vesicle nanoparticles for controlled delivery of protein drug
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Yuk, Soon Hong | - |
| dc.contributor.author | Oh, Keun Sang | - |
| dc.contributor.author | Kim, Seung Ki | - |
| dc.contributor.author | Lee, Jin Ho | - |
| dc.contributor.author | Cho, Sun Hang | - |
| dc.contributor.author | Kim, Kwangmeyung | - |
| dc.contributor.author | Jeon, Hyesung | - |
| dc.contributor.author | Kwon, Ick Chan | - |
| dc.date.accessioned | 2021-09-06T22:34:39Z | - |
| dc.date.available | 2021-09-06T22:34:39Z | - |
| dc.date.created | 2021-06-18 | - |
| dc.date.issued | 2012-03 | - |
| dc.identifier.issn | 1598-5032 | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/108995 | - |
| dc.description.abstract | The Pluronic/poly(ethylene glycol) composite nanoparticles (NPs) composed of Pluronic F-68, liquid poly(ethylene glycol) (PEG; molecular weight, 400) and human growth hormone (hGH) were stabilized with the vesicle fusion. When hGH-loaded Pluronic/PEG composite NPs were mixed with vesicles in the aqueous medium, hGH-loaded Pluronic/PEG composite NPs were incorporated into vesicles to form multi-core vesicle NPs. The morphology and size distribution of multi-core vesicle NPs were observed using field emission scanning electron microscopy, cryo-transmission electron microscopy, and a particle size analyzer. When multi-core vesicle NPs were applied as a delivery system for the protein drug, a sustained release pattern of hGH was observed. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.publisher | POLYMER SOC KOREA | - |
| dc.subject | GH-DEFICIENT PATIENTS | - |
| dc.subject | GROWTH-HORMONE GH | - |
| dc.subject | COPOLYMER | - |
| dc.subject | FUSION | - |
| dc.subject | ENCAPSULATION | - |
| dc.subject | MICROSPHERES | - |
| dc.subject | SPECTROSCOPY | - |
| dc.subject | STABILITY | - |
| dc.subject | BILAYER | - |
| dc.subject | SYSTEMS | - |
| dc.title | Multi-core vesicle nanoparticles for controlled delivery of protein drug | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Yuk, Soon Hong | - |
| dc.contributor.affiliatedAuthor | Kwon, Ick Chan | - |
| dc.identifier.doi | 10.1007/s13233-012-0053-y | - |
| dc.identifier.wosid | 000302262000013 | - |
| dc.identifier.bibliographicCitation | MACROMOLECULAR RESEARCH, v.20, no.3, pp.309 - 312 | - |
| dc.relation.isPartOf | MACROMOLECULAR RESEARCH | - |
| dc.citation.title | MACROMOLECULAR RESEARCH | - |
| dc.citation.volume | 20 | - |
| dc.citation.number | 3 | - |
| dc.citation.startPage | 309 | - |
| dc.citation.endPage | 312 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.identifier.kciid | ART001643265 | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.relation.journalResearchArea | Polymer Science | - |
| dc.relation.journalWebOfScienceCategory | Polymer Science | - |
| dc.subject.keywordPlus | GH-DEFICIENT PATIENTS | - |
| dc.subject.keywordPlus | GROWTH-HORMONE GH | - |
| dc.subject.keywordPlus | COPOLYMER | - |
| dc.subject.keywordPlus | FUSION | - |
| dc.subject.keywordPlus | ENCAPSULATION | - |
| dc.subject.keywordPlus | MICROSPHERES | - |
| dc.subject.keywordPlus | SPECTROSCOPY | - |
| dc.subject.keywordPlus | STABILITY | - |
| dc.subject.keywordPlus | BILAYER | - |
| dc.subject.keywordPlus | SYSTEMS | - |
| dc.subject.keywordAuthor | human growth hormone | - |
| dc.subject.keywordAuthor | Pluronic/PEG composite NPs | - |
| dc.subject.keywordAuthor | multi-core vesicle NPs | - |
| dc.subject.keywordAuthor | peptide drug | - |
| dc.subject.keywordAuthor | sustained release | - |
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Related Researcher
- Yuk, Soon Hong
- College of Pharmacy (Department of Pharmaceutical Science)