Antioxidative oligostilbenes from Caragana sinica
- Authors
- Jin, Qinghao; Han, Xiang Hua; Hong, Seong Su; Lee, Chul; Choe, Sanggil; Lee, Dongho; Kim, Youngsoo; Hong, Jin Tae; Lee, Mi Kyeong; Hwang, Bang Yeon
- Issue Date
- 15-1월-2012
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Caragana sinica; Fabaceae; Oligostilbenes; Antioxidant activity
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.2, pp.973 - 976
- Indexed
- SCIE
SCOPUS
- Journal Title
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Volume
- 22
- Number
- 2
- Start Page
- 973
- End Page
- 976
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/109075
- DOI
- 10.1016/j.bmcl.2011.12.012
- ISSN
- 0960-894X
- Abstract
- Two new oligostilbenes, caragasinins A (5) and B (10), and eight known compounds, kobophenol A (1), (+)-alpha-viniferin (2), (+)-ampelopsin F (3), pallidol (4), (+)-isoampelopsin F (6), miyabenol C (7), carasinaurone (8) and caraphenol B (9) were isolated from the ethylacetate-soluble extract of the roots of Caragana sinica. The structures of the isolates were determined on the basis of extensive spectroscopic analysis including 1D, 2D NMR and HRESI-MS. These compounds were assessed for antioxidant activities. Caragasinin A (5), caraphenol B (9), and caragasinin B (10) showed moderate DPPH scavenging activity and lipid peroxidation inhibitory activities with IC50 values ranging from 34.7 +/- 1.0 to 89.1 +/- 2.3 mu M. (C) 2011 Elsevier Ltd. All rights reserved.
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