Extremely Low Frequency Magnetic Fields Do Not Elicit Oxidative Stress in MCF10A Cells
DC Field | Value | Language |
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dc.contributor.author | Hong, Mi-Na | - |
dc.contributor.author | Han, Na-Kyung | - |
dc.contributor.author | Lee, Hyung-Cgul | - |
dc.contributor.author | Ko, Young-Kyu | - |
dc.contributor.author | Chi, Sung-Gil | - |
dc.contributor.author | Lee, Yun-Sil | - |
dc.contributor.author | Gimm, Yoon-Myung | - |
dc.contributor.author | Myung, Sung-Ho | - |
dc.contributor.author | Lee, Jae-Seon | - |
dc.date.accessioned | 2021-09-06T23:22:46Z | - |
dc.date.available | 2021-09-06T23:22:46Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2012-01 | - |
dc.identifier.issn | 0449-3060 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/109156 | - |
dc.description.abstract | The aim of this study was to determine whether extremely low frequency magnetic fields (ELF-MF) could affect intracellular reactive oxygen species (ROS) levels and antioxidant enzyme activity. After MCF10A human breast epithelial cells were exposed to 1 mT of 60 Hz ELF-MF for 4 hours, intracellular ROS level, superoxide dismutase (SOD) activity, and reduced to oxidized glutathione (GSH/GSSG) ratio were measured. The cells exposed to ELF-MF did not evidence statistically significant changes in the above-mentioned biological parameters as compared to either the incubator controls or sham-exposed cells. By way of contrast, the IR-exposed cells exhibited marked changes in ROS level, SOD activity, and GSH/GSSG ratio. When we assessed morphological changes and senescence-associated beta-galactosidase (SA-beta-Gal) activity, only the IR-exposed cells were positive. According to our results, it could be concluded that ELF-MF has no effect on intracellular ROS level, SOD activity, and GSH/GSSG ratio under our exposure condition. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.subject | ELECTROMAGNETIC-FIELDS | - |
dc.subject | FREE-RADICALS | - |
dc.subject | BRAIN CANCER | - |
dc.subject | BLOOD-CELLS | - |
dc.subject | DNA-DAMAGE | - |
dc.subject | EXPOSURE | - |
dc.subject | REDOX | - |
dc.subject | EXPRESSION | - |
dc.subject | INVOLVEMENT | - |
dc.title | Extremely Low Frequency Magnetic Fields Do Not Elicit Oxidative Stress in MCF10A Cells | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ko, Young-Kyu | - |
dc.contributor.affiliatedAuthor | Chi, Sung-Gil | - |
dc.identifier.doi | 10.1269/jrr.11049 | - |
dc.identifier.scopusid | 2-s2.0-84863298573 | - |
dc.identifier.wosid | 000300139200010 | - |
dc.identifier.bibliographicCitation | JOURNAL OF RADIATION RESEARCH, v.53, no.1, pp.79 - 86 | - |
dc.relation.isPartOf | JOURNAL OF RADIATION RESEARCH | - |
dc.citation.title | JOURNAL OF RADIATION RESEARCH | - |
dc.citation.volume | 53 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 79 | - |
dc.citation.endPage | 86 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Life Sciences & Biomedicine - Other Topics | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Biology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | ELECTROMAGNETIC-FIELDS | - |
dc.subject.keywordPlus | FREE-RADICALS | - |
dc.subject.keywordPlus | BRAIN CANCER | - |
dc.subject.keywordPlus | BLOOD-CELLS | - |
dc.subject.keywordPlus | DNA-DAMAGE | - |
dc.subject.keywordPlus | EXPOSURE | - |
dc.subject.keywordPlus | REDOX | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | INVOLVEMENT | - |
dc.subject.keywordAuthor | ELF-MF | - |
dc.subject.keywordAuthor | Oxidative stress | - |
dc.subject.keywordAuthor | MCF10A cells | - |
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