은이온 함유 결찰고무링의 구강 내 미생물에 대한 항균효과

Abstract

In recent days, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinfectant and biocidal material against bacteria and viruses. There is also increased interest in the nano-sized silver particles which can be used as effective bactericidal material. The purposes of this study were to investigate the effect of silverized elastomers on growth of oral pathogenic microorganisms, including Streptococcus mutans, Fusobacterium nucleatum, Porphyromonas gingivalis by comparing with conventional non-silverized elastomers. The antibacterial efficacy of silverized elastomer against oral pathogenic microbes was investigated by modified disk diffusion test and growth inhibition test. In modified disk diffusion test, silverized elastomer showed no antibacterial activity against S. mutans, F. nucleatum and P. gingivalis, In culture medium, the growth of S. mutans, F. nucleatum, P. gingivalis was not inhibited by silverized elastomer. Silverized elastomer exhibited no bacteriostatic and/or bacteriocidal effects against some experimental strain.