Different Impact of Diabetes Mellitus on In-hospital and 1-Year Mortality in Patients with Acute Myocardial Infarction Who Underwent Successful Percutaneous Coronary Intervention: Results from the Korean Acute Myocardial Infarction RegistryDifferent Impact of Diabetes Mellitus on In-hospital and 1-Year Mortality in Patients with Acute Myocardial Infarction Who Underwent Successful Percutaneous Coronary Intervention: Results from the Korean Acute Myocardial Infarction Registry
- Other Titles
- Different Impact of Diabetes Mellitus on In-hospital and 1-Year Mortality in Patients with Acute Myocardial Infarction Who Underwent Successful Percutaneous Coronary Intervention: Results from the Korean Acute Myocardial Infarction Registry
- Authors
- 박근호; 안영근; 정명호; 채성철; 허승호; 김영조; 성인환; 채제건; 홍택종; 조명찬; 배장호; 나승운; 장양수
- Issue Date
- 2012
- Publisher
- 대한내과학회
- Keywords
- Diabetes mellitus; Myocardial infarction; Mortality
- Citation
- The Korean Journal of Internal Medicine, v.27, no.2, pp.180 - 188
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean Journal of Internal Medicine
- Volume
- 27
- Number
- 2
- Start Page
- 180
- End Page
- 188
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/110082
- DOI
- 10.3904/kjim.2012.27.2.180
- ISSN
- 1226-3303
- Abstract
- Background/Aims: The aim of this study was to evaluate the impact of diabetes mellitus (DM) on in-hospital and 1-year mortality in patients who suffered acute myocardial infarction (AMI) and underwent successful percutaneous coronary intervention (PCI).
Methods: Among 5,074 consecutive patients from the Korea AMI Registry with successful revascularization between November 2005 and June 2007, 1,412 patients had a history of DM.
Results: The DM group had a higher mean age prevalence of history of hypertension, dyslipidemia, ischemic heart disease, high Killip class, and diagnoses as non-ST elevation MI than the non-DM group. Left ventricular ejection fraction (LVEF) and creatinine clearance were lower in the DM group, which also had a significantly higher incidence of in-hospital and 1-year mortality of hospital survivors (4.6% vs. 2.8%, p = 0.002; 5.0% vs. 2.5%, p < 0.001). A multivariate analysis revealed that independent predictors of in-hospital mortality were Killip class IV or III at admission, use of angiotensin converting enzyme inhibitors or angiotensin-II receptor blockers, LVEF, creatinine clearance, and a diagnosis of ST-elevated MI but not DM. However, a multivariate Cox regression analysis showed that DM was an independent predictor of 1-year mortality (hazard ratio, 1.504; 95% confidence interval, 1.032 to 2.191).
Conclusions: DM has a higher association with 1-year mortality than in-hospital mortality in patients with AMI who underwent successful PCI. Therefore, even when patients with AMI and DM undergo successful PCI, they may require further intensive treatment and continuous attention.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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