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Detecting Genetic Association and Gene-Gene Interaction using Network Analysis in Case-Control StudyDetecting Genetic Association and Gene-Gene Interaction using Network Analysis in Case-Control Study
- Other Titles
- Detecting Genetic Association and Gene-Gene Interaction using Network Analysis in Case-Control Study
- Issue Date
- 2012
- Publisher
- 한국통계학회
- Keywords
- Network analysis; genetic association; gene-gene interaction; centrality measures.
- Citation
- 응용통계연구, v.25, no.4, pp.563 - 573
- Indexed
- KCI
- Journal Title
- 응용통계연구
- Volume
- 25
- Number
- 4
- Start Page
- 563
- End Page
- 573
- ISSN
- 1225-066X
- Abstract
- Various methods of analysis have been proposed to understand the gene-disease relation and gene-gene interaction effect for a disease through comparison of genotype in case-control study. In this study, we proposed the method to detect a genetic association and gene-gene interaction through the use of a network graph and centrality measures that are used in social network analysis. The applicability of the proposed method was studied through an analysis of real genetic data.
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Collections - Graduate School > Department of Applied Statistics > 1. Journal Articles
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