Digitally tunable physicochemical coding of material composition and topography in continuous microfibres
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Edward | - |
dc.contributor.author | Jeong, Gi Seok | - |
dc.contributor.author | Choi, Yoon Young | - |
dc.contributor.author | Lee, Kwang Ho | - |
dc.contributor.author | Khademhosseini, Ali | - |
dc.contributor.author | Lee, Sang-Hoon | - |
dc.date.accessioned | 2021-09-07T06:37:02Z | - |
dc.date.available | 2021-09-07T06:37:02Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2011-11 | - |
dc.identifier.issn | 1476-1122 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/111237 | - |
dc.description.abstract | Heterotypic functional materials with compositional and topographical properties that vary spatiotemporally on the micro- or nanoscale are common in nature. However, fabricating such complex materials in the laboratory remains challenging. Here we describe a method to continuously create microfibres with tunable morphological, structural and chemical features using a microfluidic system consisting of a digital, programmable flow control that mimics the silk-spinning process of spiders. With this method we fabricated hydrogel microfibres coded with varying chemical composition and topography along the fibre, including gas micro- bubbles as well as nanoporous spindle-knots and joints that enabled directional water collection. We also explored the potential use of the coded microfibres for tissue engineering applications by creating multifunctional microfibres with a spatially controlled co-culture of encapsulated cells. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | DRUG-DELIVERY | - |
dc.subject | FIBERS | - |
dc.subject | GENERATION | - |
dc.subject | SCAFFOLDS | - |
dc.subject | FLOW | - |
dc.title | Digitally tunable physicochemical coding of material composition and topography in continuous microfibres | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jeong, Gi Seok | - |
dc.contributor.affiliatedAuthor | Lee, Sang-Hoon | - |
dc.identifier.doi | 10.1038/NMAT3108 | - |
dc.identifier.scopusid | 2-s2.0-80054956005 | - |
dc.identifier.wosid | 000296540900019 | - |
dc.identifier.bibliographicCitation | NATURE MATERIALS, v.10, no.11, pp.877 - 883 | - |
dc.relation.isPartOf | NATURE MATERIALS | - |
dc.citation.title | NATURE MATERIALS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 877 | - |
dc.citation.endPage | 883 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | FIBERS | - |
dc.subject.keywordPlus | GENERATION | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | FLOW | - |
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