Single Cystathionine beta-Synthase Domain-Containing Proteins Modulate Development by Regulating the Thioredoxin System in Arabidopsis
DC Field | Value | Language |
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dc.contributor.author | Yoo, Kyoung Shin | - |
dc.contributor.author | Ok, Sung Han | - |
dc.contributor.author | Jeong, Byung-Cheon | - |
dc.contributor.author | Jung, Kwang Wook | - |
dc.contributor.author | Cui, Mei Hua | - |
dc.contributor.author | Hyoung, Sujin | - |
dc.contributor.author | Lee, Myeong-Ryeol | - |
dc.contributor.author | Song, Hyun Kyu | - |
dc.contributor.author | Shin, Jeong Sheop | - |
dc.date.accessioned | 2021-09-07T07:49:36Z | - |
dc.date.available | 2021-09-07T07:49:36Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2011-10 | - |
dc.identifier.issn | 1040-4651 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/111465 | - |
dc.description.abstract | Plant thioredoxins (Trxs) participate in two redox systems found in different cellular compartments: the NADP-Trx system (NTS) in the cytosol and mitochondria and the ferredoxin-Trx system (FTS) in the chloroplast, where they function as redox regulators by regulating the activity of various target enzymes. The identities of the master regulators that maintain cellular homeostasis and modulate timed development through redox regulating systems have remained completely unknown. Here, we show that proteins consisting of a single cystathionine beta-synthase (CBS) domain pair stabilize cellular redox homeostasis and modulate plant development via regulation of Trx systems by sensing changes in adenosine-containing ligands. We identified two CBS domain-containing proteins in Arabidopsis thaliana, CBSX1 and CBSX2, which are localized to the chloroplast, where they activate all four Trxs in the FTS. CBSX3 was found to regulate mitochondrial Trx members in the NTS. CBSX1 directly regulates Trxs and thereby controls H2O2 levels and regulates lignin polymerization in the anther endothecium. It also affects plant growth by regulating Calvin cycle enzymes, such as malate dehydrogenase, via homeostatic regulation of Trxs. Based on our findings, we suggest that the CBSX proteins (or a CBS pair) are ubiquitous redox regulators that regulate Trxs in the FTS and NTS to modulate development and maintain homeostasis under conditions that are threatening to the cell. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER SOC PLANT BIOLOGISTS | - |
dc.subject | JASMONIC ACID BIOSYNTHESIS | - |
dc.subject | MALE-STERILE MUTANT | - |
dc.subject | ANTHER DEHISCENCE | - |
dc.subject | PLANT-MITOCHONDRIA | - |
dc.subject | HYDROGEN-PEROXIDE | - |
dc.subject | CRYSTAL-STRUCTURE | - |
dc.subject | CHLORIDE CHANNEL | - |
dc.subject | GENE ENCODES | - |
dc.subject | AMP-BINDING | - |
dc.subject | REDUCTASE | - |
dc.title | Single Cystathionine beta-Synthase Domain-Containing Proteins Modulate Development by Regulating the Thioredoxin System in Arabidopsis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Hyun Kyu | - |
dc.contributor.affiliatedAuthor | Shin, Jeong Sheop | - |
dc.identifier.doi | 10.1105/tpc.111.089847 | - |
dc.identifier.scopusid | 2-s2.0-82755191515 | - |
dc.identifier.wosid | 000298175900005 | - |
dc.identifier.bibliographicCitation | PLANT CELL, v.23, no.10, pp.3577 - 3594 | - |
dc.relation.isPartOf | PLANT CELL | - |
dc.citation.title | PLANT CELL | - |
dc.citation.volume | 23 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 3577 | - |
dc.citation.endPage | 3594 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordPlus | JASMONIC ACID BIOSYNTHESIS | - |
dc.subject.keywordPlus | MALE-STERILE MUTANT | - |
dc.subject.keywordPlus | ANTHER DEHISCENCE | - |
dc.subject.keywordPlus | PLANT-MITOCHONDRIA | - |
dc.subject.keywordPlus | HYDROGEN-PEROXIDE | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURE | - |
dc.subject.keywordPlus | CHLORIDE CHANNEL | - |
dc.subject.keywordPlus | GENE ENCODES | - |
dc.subject.keywordPlus | AMP-BINDING | - |
dc.subject.keywordPlus | REDUCTASE | - |
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