Different therapeutic responses in chronic obstructive pulmonary disease subgroups
DC Field | Value | Language |
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dc.contributor.author | Lee, J. S. | - |
dc.contributor.author | Huh, J. W. | - |
dc.contributor.author | Chae, E. J. | - |
dc.contributor.author | Seo, J. B. | - |
dc.contributor.author | Ra, S. W. | - |
dc.contributor.author | Lee, J-H. | - |
dc.contributor.author | Kim, E-K. | - |
dc.contributor.author | Lee, Y. K. | - |
dc.contributor.author | Kim, T-H. | - |
dc.contributor.author | Kim, W. J. | - |
dc.contributor.author | Lee, J. H. | - |
dc.contributor.author | Lee, S-M. | - |
dc.contributor.author | Lee, S. | - |
dc.contributor.author | Lim, S. Y. | - |
dc.contributor.author | Shin, T. R. | - |
dc.contributor.author | Yoon, H. I. | - |
dc.contributor.author | Sheen, S. S. | - |
dc.contributor.author | Oh, Y-M. | - |
dc.contributor.author | Lee, S-D. | - |
dc.date.accessioned | 2021-09-07T10:02:54Z | - |
dc.date.available | 2021-09-07T10:02:54Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2011-08 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/111938 | - |
dc.description.abstract | SETTING: Eleven referring hospitals in South Korea. OBJECTIVE: To compare therapeutic responses in chronic obstructive pulmonary disease (COPD) subgroups, classified by diffusing capacity of the lung for carbon monoxide (DLCO) and lung volume. DESIGN: A total of 130 stable male COPD patients were classified into four subgroups according to baseline DLCO and residual volume/total lung capacity (RV/TLC) ratio. We compared therapeutic responses to short acting beta(2)-agonist (SABA) and 3-month combined inhalation of long-acting beta(2)-agonist (LABA) and corticosteroid among patients with these subgroups. RESULTS: Among the 130 COPD patients, 41 (31.5%) had normal DLCO and RV/TLC, 28 (21.5%) low DLCO and normal RV/TLC, 31 (23.8%) normal DLCO and high RV/TLC, and 30 (23.1%) low DLCO and high RV/TLC. The normal DLCO/high RV/TLC subgroup showed a significantly larger flow response (changes in forced expiratory volume in 1 s) to salbutamol than the normal DLCO/RV/TLC subgroups, and a larger volume response (changes in forced vital capacity) than the two normal RV/TLC subgroups. The normal DLCO/high RV/TLC subgroup also showed significantly larger flow and volume response to 3-month combined inhalation of LABA and corticosteroid than the two normal RV/TLC subgroups. CONCLUSION: COPD subgroups classified by DLco and RV/TLC may have different pulmonary function responses to pharmacological treatment. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D) | - |
dc.subject | LUNG-FUNCTION | - |
dc.subject | SALMETEROL/FLUTICASONE PROPIONATE | - |
dc.subject | EMPHYSEMA | - |
dc.subject | PREVENTION | - |
dc.subject | DENSITY | - |
dc.subject | VOLUMES | - |
dc.subject | AGONIST | - |
dc.title | Different therapeutic responses in chronic obstructive pulmonary disease subgroups | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, S. | - |
dc.identifier.doi | 10.5588/ijtld.10.0553 | - |
dc.identifier.scopusid | 2-s2.0-79960426876 | - |
dc.identifier.wosid | 000293678000017 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, v.15, no.8, pp.1104 - 1110 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.citation.title | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.citation.volume | 15 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1104 | - |
dc.citation.endPage | 1110 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | LUNG-FUNCTION | - |
dc.subject.keywordPlus | SALMETEROL/FLUTICASONE PROPIONATE | - |
dc.subject.keywordPlus | EMPHYSEMA | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | DENSITY | - |
dc.subject.keywordPlus | VOLUMES | - |
dc.subject.keywordPlus | AGONIST | - |
dc.subject.keywordAuthor | COPD | - |
dc.subject.keywordAuthor | diffusing capacity | - |
dc.subject.keywordAuthor | emphysema | - |
dc.subject.keywordAuthor | lung volume | - |
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