Reduced striatal dopamine D2 receptors in people with Internet addiction
- Authors
- Kim, Sang Hee; Baik, Sang-Hyun; Park, Chang Soo; Kim, Su Jin; Choi, Sung Won; Kim, Sang Eun
- Issue Date
- 11-6월-2011
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- caudate; [C-11]raclopride; dopamine D2 receptor; internet addiction; PET; putamen; striatum
- Citation
- NEUROREPORT, v.22, no.8, pp.407 - 411
- Indexed
- SCIE
SCOPUS
- Journal Title
- NEUROREPORT
- Volume
- 22
- Number
- 8
- Start Page
- 407
- End Page
- 411
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/112234
- DOI
- 10.1097/WNR.0b013e328346e16e
- ISSN
- 0959-4965
- Abstract
- An increasing amount of research has suggested that Internet addiction is associated with abnormalities in the dopaminergic brain system. We hypothesized that Internet addiction would be associated with reduced levels of dopaminergic receptor availability in the striatum compared with controls. To test this hypothesis, a radiolabeled ligand [C-11]raclopride and positron emission tomography was used to assess dopamine D2 receptor binding potential in men with and without Internet addiction. Consistent with our prediction, individuals with Internet addiction showed reduced levels of dopamine D2 receptor availability in subdivisions of the striatum including the bilateral dorsal caudate and right putamen. This finding contributes to the understanding of neurobiological mechanism of Internet addiction. NeuroReport 22:407-411 (C) 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
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Collections - Graduate School > Department of Brain and Cognitive Engineering > 1. Journal Articles
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