Pulmonary artery pressure in chronic obstructive pulmonary disease without resting hypoxaemia
DC Field | Value | Language |
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dc.contributor.author | Lee, J. H. | - |
dc.contributor.author | Oh, Y-M. | - |
dc.contributor.author | Seo, J. B. | - |
dc.contributor.author | Lee, Y. K. | - |
dc.contributor.author | Kim, W. J. | - |
dc.contributor.author | Sheen, S. S. | - |
dc.contributor.author | Kim, T-H. | - |
dc.contributor.author | Lee, J-H. | - |
dc.contributor.author | Kim, E-K. | - |
dc.contributor.author | Lee, J. S. | - |
dc.contributor.author | Huh, J. W. | - |
dc.contributor.author | Lim, S. Y. | - |
dc.contributor.author | Yoon, H. I. | - |
dc.contributor.author | Shin, T. R. | - |
dc.contributor.author | Lee, S-M. | - |
dc.contributor.author | Lee, S. Y. | - |
dc.contributor.author | Lee, S-D. | - |
dc.date.accessioned | 2021-09-07T12:05:40Z | - |
dc.date.available | 2021-09-07T12:05:40Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2011-06 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/112357 | - |
dc.description.abstract | BACKGROUND: Chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension and cor pulmonale, which are predictors of mortality. OBJECTIVE: To identify predictors of increased pulmonary artery pressure (PAP) in COPD patients without resting hypoxaemia, and to characterise COPD patients with increased PAP. DESIGN: A study of 117 COPD patients from the Korean Obstructive Lung Disease (KOLD) cohort who had measurable tricuspid regurgitant flow under transthoracic Doppler echocardiography and no resting hypoxaemia. RESULTS: The mean patient age was 67 years. Mean forced expiratory volume in 1 second (FEV1) was 47% predicted, mean haemoglobin (Hb) concentration was 145 g/l and mean systolic PAP (sPAP) was 33 mmHg. Multiple linear regression analysis showed that Hb was the only factor independently associated with sPAP (beta = -1.752,P = 0.005). Cluster analysis using FEV1% predicted, sPAP and Hb concentration as variables indicated three patient clusters: Cluster 1 (n = 36; mean FEV1 44% predicted, mean sPAP 39 mmHg, mean Hb 132 g/l), Cluster 2 (n = 45; FEV1 35% predicted, sPAP 31 mmHg, Hb 154 g/l), and Cluster 3 (n = 36; FEAT, 65% predicted, sPAP 29 mmHg, Hb 148 g/l). CONCLUSION: Elevated PAP was linked to low haemoglobin levels in COPD without resting hypoxaemia. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D) | - |
dc.subject | SYSTOLIC PRESSURE | - |
dc.subject | VASCULAR-DISEASE | - |
dc.subject | HYPERTENSION | - |
dc.subject | COPD | - |
dc.subject | POLYCYTHEMIA | - |
dc.subject | OXYGEN | - |
dc.subject | HEMOGLOBIN | - |
dc.subject | EMPHYSEMA | - |
dc.subject | EXERCISE | - |
dc.title | Pulmonary artery pressure in chronic obstructive pulmonary disease without resting hypoxaemia | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, S. Y. | - |
dc.identifier.doi | 10.5588/ijtld.10.0598 | - |
dc.identifier.scopusid | 2-s2.0-79955845689 | - |
dc.identifier.wosid | 000293724800022 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, v.15, no.6, pp.830 - 837 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.citation.title | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.citation.volume | 15 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 830 | - |
dc.citation.endPage | 837 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | EMPHYSEMA | - |
dc.subject.keywordPlus | EXERCISE | - |
dc.subject.keywordPlus | SYSTOLIC PRESSURE | - |
dc.subject.keywordPlus | VASCULAR-DISEASE | - |
dc.subject.keywordPlus | HYPERTENSION | - |
dc.subject.keywordPlus | COPD | - |
dc.subject.keywordPlus | POLYCYTHEMIA | - |
dc.subject.keywordPlus | OXYGEN | - |
dc.subject.keywordPlus | HEMOGLOBIN | - |
dc.subject.keywordAuthor | COPD | - |
dc.subject.keywordAuthor | echocardiography | - |
dc.subject.keywordAuthor | haemoglobin | - |
dc.subject.keywordAuthor | pulmonary artery pressure | - |
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