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Coumarin-Based Thiol Chemosensor: Synthesis, Turn-On Mechanism, and Its Biological Application
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jung, Hyo Sung | - |
| dc.contributor.author | Ko, Kyoung Chul | - |
| dc.contributor.author | Kim, Gun-Hee | - |
| dc.contributor.author | Lee, Ah-Rah | - |
| dc.contributor.author | Na, Yun-Cheol | - |
| dc.contributor.author | Kang, Chulhun | - |
| dc.contributor.author | Lee, Jin Yong | - |
| dc.contributor.author | Kim, Jong Seung | - |
| dc.date.accessioned | 2021-09-07T14:06:32Z | - |
| dc.date.available | 2021-09-07T14:06:32Z | - |
| dc.date.created | 2021-06-14 | - |
| dc.date.issued | 2011-03-18 | - |
| dc.identifier.issn | 1523-7060 | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/112835 | - |
| dc.description.abstract | A new chemodosimetric probe (1) is reported that selectively detects thiols over other relevant biological species by the turning on of its fluorescence through a Michael type reaction. The fluorogenic process upon its reaction was revealed to be mediated by intramolecular charge transfer, as confirmed by time-dependent density functional theory calculations. The application of probe 1 to cells is also examined by confocal microscopy, and its cysteine preference was observed by an ex vivo LC-MS analysis of the cellular metabolite. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.publisher | AMER CHEMICAL SOC | - |
| dc.subject | FLUORESCENT | - |
| dc.subject | CYSTEINE | - |
| dc.subject | GLUTATHIONE | - |
| dc.subject | PROBE | - |
| dc.subject | HOMOCYSTEINE | - |
| dc.subject | RHODAMINE | - |
| dc.subject | PLASMA | - |
| dc.subject | WATER | - |
| dc.subject | IONS | - |
| dc.title | Coumarin-Based Thiol Chemosensor: Synthesis, Turn-On Mechanism, and Its Biological Application | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Kim, Jong Seung | - |
| dc.identifier.doi | 10.1021/ol2001864 | - |
| dc.identifier.scopusid | 2-s2.0-79952592188 | - |
| dc.identifier.wosid | 000288148800060 | - |
| dc.identifier.bibliographicCitation | ORGANIC LETTERS, v.13, no.6, pp.1498 - 1501 | - |
| dc.relation.isPartOf | ORGANIC LETTERS | - |
| dc.citation.title | ORGANIC LETTERS | - |
| dc.citation.volume | 13 | - |
| dc.citation.number | 6 | - |
| dc.citation.startPage | 1498 | - |
| dc.citation.endPage | 1501 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.subject.keywordPlus | FLUORESCENT | - |
| dc.subject.keywordPlus | CYSTEINE | - |
| dc.subject.keywordPlus | GLUTATHIONE | - |
| dc.subject.keywordPlus | PROBE | - |
| dc.subject.keywordPlus | HOMOCYSTEINE | - |
| dc.subject.keywordPlus | RHODAMINE | - |
| dc.subject.keywordPlus | PLASMA | - |
| dc.subject.keywordPlus | WATER | - |
| dc.subject.keywordPlus | IONS | - |
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