Gamma Knife surgery for subependymal giant cell astrocytomas Clinical article
DC Field | Value | Language |
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dc.contributor.author | Park, Kyung-Jae | - |
dc.contributor.author | Kano, Hideyuki | - |
dc.contributor.author | Kondziolka, Douglas | - |
dc.contributor.author | Niranjan, Ajay | - |
dc.contributor.author | Flickinger, John C. | - |
dc.contributor.author | Lunsford, L. Dade | - |
dc.date.accessioned | 2021-09-07T14:30:01Z | - |
dc.date.available | 2021-09-07T14:30:01Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2011-03 | - |
dc.identifier.issn | 0022-3085 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/112920 | - |
dc.description.abstract | Object. The authors report their experience of using Gamma Knife surgery (GKS) in patients with subependymal giant cell astrocytoma (SEGA). Methods. Over a 20-year period, the authors identified 6 patients with SEGAs who were eligible for GKS. The median patient age was 16.5 years (range 7-55 years). In 4 patients, GKS was used as a primary management therapy. One patient underwent radiosurgery for recurrent tumors after prior resection, and in 1 patient GKS was used as an adjunct after subtotal resection. The median tumor volume at GKS was 2.75 cm(3) (range 0.7-5.9 cm(3)). A median radiation dose of 14 Gy (range 11-20 Gy) was delivered to the tumor margin. Results. The median follow-up duration was 73 months (range 42-90 months). Overall local tumor control was achieved in 4 tumors (67%) with progression-free periods of 24, 42. 57, and 66 months. Three tumors regressed and one remained unchanged. In 2 patients the tumors progressed, and in 1 of these patients the lesion was managed by repeated GKS with subsequent tumor regression. The other relatively large tumor (5.9 cm(3)) was excised 9 months after GKS. The progression-free period for all GKS-managed tumors varied from 9 to 66 months. There were no cases of hydrocephalus or GKS-related morbidity. Conclusions. Gamma Knife surgery may be an additional minimally invasive management option for SEGA in a patient who harbors a small but progressively enlarging tumor when complete resection is not safely achievable. It may also benefit patients with a residual or recurrent tumor that has progressed after surgery. (DOI: 10.3171/2010.9.JNS10816) | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER ASSOC NEUROLOGICAL SURGEONS | - |
dc.subject | LOW-GRADE ASTROCYTOMAS | - |
dc.subject | TUBEROUS SCLEROSIS | - |
dc.subject | INTRAVENTRICULAR TUMORS | - |
dc.subject | RADIOSURGERY | - |
dc.subject | CHILDREN | - |
dc.title | Gamma Knife surgery for subependymal giant cell astrocytomas Clinical article | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Kyung-Jae | - |
dc.identifier.doi | 10.3171/2010.9.JNS10816 | - |
dc.identifier.scopusid | 2-s2.0-79952274305 | - |
dc.identifier.wosid | 000287676700046 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROSURGERY, v.114, no.3, pp.808 - 813 | - |
dc.relation.isPartOf | JOURNAL OF NEUROSURGERY | - |
dc.citation.title | JOURNAL OF NEUROSURGERY | - |
dc.citation.volume | 114 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 808 | - |
dc.citation.endPage | 813 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | LOW-GRADE ASTROCYTOMAS | - |
dc.subject.keywordPlus | TUBEROUS SCLEROSIS | - |
dc.subject.keywordPlus | INTRAVENTRICULAR TUMORS | - |
dc.subject.keywordPlus | RADIOSURGERY | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordAuthor | Gamma Knife surgery | - |
dc.subject.keywordAuthor | glioma | - |
dc.subject.keywordAuthor | radiosurgery | - |
dc.subject.keywordAuthor | subependymal giant cell astrocytoma | - |
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