Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers
DC Field | Value | Language |
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dc.contributor.author | Lee, Kyung-Hea | - |
dc.contributor.author | Park, Eunju | - |
dc.contributor.author | Lee, Hye-Jin | - |
dc.contributor.author | Kim, Myeong-Ok | - |
dc.contributor.author | Cha, Yong-Jun | - |
dc.contributor.author | Kim, Jung-Mi | - |
dc.contributor.author | Lee, Hyeran | - |
dc.contributor.author | Shin, Min-Jeong | - |
dc.date.accessioned | 2021-09-07T15:52:27Z | - |
dc.date.available | 2021-09-07T15:52:27Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2011-02 | - |
dc.identifier.issn | 1976-1457 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/113210 | - |
dc.description.abstract | Limited information from human studies indicates that dietary quercetin supplementation influences blood lipid profiles, glycemic response, and inflammatory status, collectively termed cardiometabolic risks. We tested the hypothesis that quercetin-rich supplementation, derived from onion peel extract, improves cardiometabolic risk components in healthy male smokers in a randomized, double blinded, placebo-controlled parallel design. Randomly assigned subjects were instructed to take either the placebo (n=43) or 100 mg quercetin capsules each day (n=49) for 10 weeks. Anthropometric parameters and blood pressure were measured, and blood lipids, glucose, interleukin-6, and soluble vascular cell adhesion molecule-1 (sVCAM-1) were determined at baseline and after 10 weeks of quercetin supplementation. Quercetin-rich supplementation significantly reduced serum concentrations of total cholesterol (P<0.05) and LDL-cholesterol (P<0.01), whereas these effects were not shown in the placebo group. Furthermore, significant increases were observed in serum concentrations of HDL-cholesterol both in the placebo (P<0.005) and quercetin-rich supplementation group (P<0.001); however, changes in HDL-cholesterol were significantly greater in subjects receiving quercetin-rich supplementation than the placebo. Both systolic (P<0.05) and diastolic blood pressure (P<0.01) decreased significantly in the quercetin-rich supplementation group. Glucose concentrations decreased significantly after 10 weeks of quercetin-rich supplementation (P<0.05). In contrast, no effects of quercetin-rich supplementation were observed for the inflammatory markers-IL-6 and sVCAM-1. Daily quercetin-rich supplementation from onion peel extract improved blood lipid profiles, glucose, and blood pressure, suggesting a beneficial role for quercetin as a preventive measure against cardiovascular risk. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN NUTRITION SOC | - |
dc.subject | OXIDATIVE DNA-DAMAGE | - |
dc.subject | BLOOD-PRESSURE | - |
dc.subject | FLAVONOID QUERCETIN | - |
dc.subject | LIPID-PEROXIDATION | - |
dc.subject | FATTY-ACID | - |
dc.subject | CHOLESTEROL | - |
dc.subject | ANTIOXIDANT | - |
dc.subject | POLYPHENOLS | - |
dc.subject | DISEASE | - |
dc.subject | WOMEN | - |
dc.title | Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Min-Jeong | - |
dc.identifier.doi | 10.4162/nrp.2011.5.1.28 | - |
dc.identifier.scopusid | 2-s2.0-79955583955 | - |
dc.identifier.wosid | 000287956000004 | - |
dc.identifier.bibliographicCitation | NUTRITION RESEARCH AND PRACTICE, v.5, no.1, pp.28 - 33 | - |
dc.relation.isPartOf | NUTRITION RESEARCH AND PRACTICE | - |
dc.citation.title | NUTRITION RESEARCH AND PRACTICE | - |
dc.citation.volume | 5 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 28 | - |
dc.citation.endPage | 33 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001530598 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | OXIDATIVE DNA-DAMAGE | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | FLAVONOID QUERCETIN | - |
dc.subject.keywordPlus | LIPID-PEROXIDATION | - |
dc.subject.keywordPlus | FATTY-ACID | - |
dc.subject.keywordPlus | CHOLESTEROL | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | POLYPHENOLS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordAuthor | Quercetin | - |
dc.subject.keywordAuthor | onion | - |
dc.subject.keywordAuthor | cardiometabolic risks | - |
dc.subject.keywordAuthor | dyslipidemia | - |
dc.subject.keywordAuthor | inflammation | - |
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