Angiomyolipoma of the lower lip: A case report and review of the published work

Abstract

Angiomyolipoma (AML) in the oral cavity is extremely rare. Their histological features are characterized by admixtures of blood vessels, smooth muscles and mature adipose tissues. We report a case of sporadic AML in the lower lip of a 56-year-old man. Clinically, it presented as a mucocele-like lesion. An excised specimen showed a well-circumscribed, 1.3 cm × 1.0 cm × 0.8 cm-sized, yellowish mass, composed of blood vessels, smooth muscles and mature adipose tissues. These were not epithelioid cells and immunohistochemical stain for human melanoma black (HMB)-45 was negative. Extrarenal AML usually is not associated with tuberous sclerosis and has no HMB-45 immunoreactive cells although it shares the terminology with renal AML. It is regarded as benign. Surgical excision is considered curative. Copyright © 2011 The Korean Society for Cytopathology, The Korean Society for Legal Medicine, The Korean Society of Oral and Maxillofacial Pathology, The Korean Society of Pathologists, The Korean Society of Toxicological Pathology, The Korean Society of Veterinary Pathology and Blackwell Publishing Asia Pty Ltd.