IgG4-related inflammatory pseudotumor of the lung, a pulmonary manifestation of the IgG4-related sclerosing disease
- Authors
- Kim, Y.; Jeong, H.; Kim, A.; Kim, H.K.; Shin, B.K.
- Issue Date
- 2011
- Keywords
- Autoimmune pancreatitis; Immunoglobulin g; Lung; Plasma cell granuloma; Pulmonary
- Citation
- Basic and Applied Pathology, v.4, no.1, pp.14 - 17
- Indexed
- SCOPUS
- Journal Title
- Basic and Applied Pathology
- Volume
- 4
- Number
- 1
- Start Page
- 14
- End Page
- 17
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/114684
- DOI
- 10.1111/j.1755-9294.2011.01098.x
- ISSN
- 1755-9294
- Abstract
- We report a case of IgG4-related inflammatory pseudotumor of lung, which coexisted with autoimmune pancreatitis. A 65-year-old man was admitted with left lung mass and left upper abdominal pain. A biopsy was performed for the lung mass under suspicion of malignancy. Microscopic examination demonstrated the proliferation of spindle cells, fibrosis and heavy infiltration of plasma cells, which were strongly immunoreactive for IgG4. Diffusely enlarged pancreas in abdominal computed tomography scan and elevated serum IgG4 level suggested the patient also had an autoimmune pancreatitis. We concluded this patient had the pulmonary inflammatory pseudotumor, as well as the autoimmune pancreatitis. These features were manifestations of the so-called IgG4-related sclerosing disease, which is a recently proposed clinicopathological entity, characterized by extensive IgG4-positive plasma cell infiltration and sclerosing inflammation in various organs. Copyright © 2011 The Korean Society for Cytopathology, The Korean Society for Legal Medicine, The Korean Society of Oral and Maxillofacial Pathology, The Korean Society of Pathologists, The Korean Society of Toxicological Pathology, The Korean Society of Veterinary Pathology and Blackwell Publishing Asia Pty Ltd.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.