Highly-stable magnetically-separable organic-inorganic hybrid microspheres for enzyme entrapment

Abstract

Organic-inorganic hybrid microspheres for a magnetically separable and highly stable enzyme system were successfully fabricated. After enzymes were entrapped, these hybrid microspheres were found to be highly stable for more than 120 days with about 75% of the initial activity preserved, and were successfully reused more than 10 times repeatedly. Furthermore, magnet-based separation was also found to be successful for the repeated usage.