Immunotoxicity activity of 2,6,10,15-tetrame-heptadecane from the essential oils of Clerodendron trichotomum Thunb. against Aedes aegypti L
- Authors
- Lee, Sung-Jae; Moon, Hyung-In
- Issue Date
- 12월-2010
- Publisher
- INFORMA HEALTHCARE
- Keywords
- Aedes aegypti; Clerodendron trichotomum; essential oils; immunotoxicity effects
- Citation
- IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, v.32, no.4, pp.705 - 707
- Indexed
- SCIE
SCOPUS
- Journal Title
- IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Volume
- 32
- Number
- 4
- Start Page
- 705
- End Page
- 707
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/115159
- DOI
- 10.3109/08923971003685959
- ISSN
- 0892-3973
- Abstract
- The leaf parts of Clerodendron trichotomum were extracted and the major essential oils composition and immunotoxicity effects were studied. The analyses were conducted by gas chromatography-mass spectroscopy (GC-MS) revealed that the essential oils of C. trichotomum (CTEO). The CTEO yield was 0.071%, and GC/MS analysis revealed that its major constituents were Hexanal (3.31%), 5-Me-3-heptanone (1.71%), 2,6,6-trime-cyclohexanone (2.23%), 2,6,10,15-tetrame-heptadecane (24.21%) and Linalool (31.2%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC(50) value of 32.78 ppm and an LC(90) value of 93.72 ppm. 2,6,10,15-tetrame-heptadecane was the most toxic among the two major components (2,6,10,15-tetrame-heptadecane and Linalool), with an LC(50) value near 43.9 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxicity agents against A. aegypti.</.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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