Resistin Concentration is Increased in the Peritoneal Fluid of Women with Endometriosis
- Authors
- Yi, Kyong Wook; Shin, Jung-Ho; Park, Hyun Tae; Kim, Tak; Kim, Sun Haeng; Hur, Jun-Young
- Issue Date
- 11월-2010
- Publisher
- WILEY-BLACKWELL
- Keywords
- Endometriosis; peritoneal fluid; resistin
- Citation
- AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, v.64, no.5, pp.318 - 323
- Indexed
- SCIE
SCOPUS
- Journal Title
- AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Volume
- 64
- Number
- 5
- Start Page
- 318
- End Page
- 323
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/115367
- DOI
- 10.1111/j.1600-0897.2010.00840.x
- ISSN
- 1046-7408
- Abstract
- Problem The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis. Method of study PF sampling was obtained from women with (n = 48) and without endometriosis (n = 36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay. Results The mean concentration of PF resistin was significantly higher in women with endometriosis compared to the controls. PF resistin concentrations were not associated with any of the anthropometric indices. The PF adiponectin did not differ between the two groups, but showed a significant association with the weight, body mass index, and hip circumference. After adjusting for these factors, PF adiponectin expression was not associated with endometriosis. Conclusion The findings of this study suggest a potent role for resistin in endometriosis. Further studies are needed to elucidate the biological implications of resistin in endometriosis.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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